Chromosomal Disorders

The video tutorial explains chromosomal mutations, including changes in structure and number, known as chromosomal aberrations. It covers types of rearrangements like deletion, duplication, translocation, and inversion. Heteroploidy, involving changes in chromosome numbers, is divided into euploidy and aneuploidy. Euploidy includes monoploidy and polyploidy, while aneuploidy includes hyperploidy and hypoploidy. The tutorial also discusses chromosomal disorders such as Down syndrome, Turner syndrome, and Klinefelter syndrome, highlighting their causes and characteristics.

What is a chromosomal aberration?

What causes chromosomal rearrangements or aberrations?

Explain the difference between euploidy and aneuploidy.

How does nondisjunction lead to aneuploidy?

What are the physical characteristics of individuals with Down syndrome?

Describe the Turner syndrome and its karyotype.

What is Klinefelter syndrome and how does it affect males?