Preparation of Amines: Reduction of nitro compounds

Preparation of Amines: Reduction of nitro compounds

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Chemistry

11th - 12th Grade

Hard

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The video tutorial covers six methods for preparing amines: reduction of nitro compounds, ammonolysis of alkyl halides, reduction of nitriles and amides, Gabriel phthalimide synthesis, and Hofmann bromide degradation. Each method is explained with its process, advantages, and limitations. The reduction of nitro compounds involves hydrogenation, while ammonolysis can lead to a mixture of amines. Reduction of nitriles and amides uses lithium aluminum hydride. Gabriel synthesis is specific for primary amines, and Hofmann degradation results in a primary amine with one less carbon atom.

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7 questions

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1.

OPEN ENDED QUESTION

3 mins • 1 pt

What are the six methods of preparation of amines mentioned in the text?

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2.

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3 mins • 1 pt

Explain the process of reduction of nitro compounds to obtain amines.

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3.

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3 mins • 1 pt

What is ammonolysis of alkyl halides and how does it lead to the formation of amines?

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4.

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3 mins • 1 pt

What are the drawbacks of ammonolysis in the preparation of amines?

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5.

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3 mins • 1 pt

Describe the reduction of nitriles and the type of amine produced.

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6.

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3 mins • 1 pt

What is the Gabriel thalamic synthesis and how is it used to prepare primary amines?

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7.

OPEN ENDED QUESTION

3 mins • 1 pt

Explain the Hoffman bromide degradation reaction and its significance in amine preparation.

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