Purine Nucleoside Phosphorylase: Physiology, Biochemistry, and Mechanism

The video explores purine catabolism, focusing on the degradation of adenosine to inosine and hypoxanthine. It details the role and mechanism of purine nucleoside phosphorylase, including its substrates and reaction steps. The video also discusses the impact of arsenate on enzyme activity and its detoxification process, highlighting the enzyme's ability to reduce arsenate to arsenite.

What are the substrates that purine nucleoside phosphorylase can act upon?

Describe the mechanism of action of purine nucleoside phosphorylase.

What role does arsenate play in nucleotide catabolism according to the text?

How does the enzyme purine nucleoside phosphorylase detoxify arsenate?