Ketone Body Biosynthesis

Ketone Body Biosynthesis

Assessment

Interactive Video

Science, Chemistry, Health Sciences, Biology

University

Hard

Created by

Wayground Content

FREE Resource

The video tutorial explains the three ketone bodies: acetone, acetoacetate, and beta hydroxybutyrate. It discusses their production when glucose metabolism is low, such as during fasting or in diabetes. The biosynthesis process starts with acetyl CoA and involves enzymes like thiolase and HMG CoA synthase. Acetoacetate can be converted to acetone or beta hydroxybutyrate, with clinical relevance in conditions like diabetic ketoacidosis. The liver synthesizes ketone bodies but cannot catabolize them.

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10 questions

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1.

OPEN ENDED QUESTION

3 mins • 1 pt

What are the three types of ketone bodies mentioned in the text?

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2.

OPEN ENDED QUESTION

3 mins • 1 pt

Explain the process that leads to the production of ketone bodies when glucose is not metabolized.

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3.

OPEN ENDED QUESTION

3 mins • 1 pt

What role does insulin play in the metabolism of glucose and the production of ketone bodies?

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4.

OPEN ENDED QUESTION

3 mins • 1 pt

Describe the initial steps in the biosynthesis of ketone bodies starting from acetyl CoA.

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5.

OPEN ENDED QUESTION

3 mins • 1 pt

What is the significance of the enzyme HMG CoA synthase in ketone body biosynthesis?

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6.

OPEN ENDED QUESTION

3 mins • 1 pt

How does acetoacetate lead to the formation of acetone?

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7.

OPEN ENDED QUESTION

3 mins • 1 pt

What are the two fates of acetoacetate as described in the text?

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