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X Inactivation

X Inactivation

Assessment

Interactive Video

Biology, Engineering

11th Grade - University

Hard

Created by

Wayground Content

FREE Resource

The podcast discusses X inactivation, also known as lyonization, named after Mary Lyon. It explains why calico and tortoiseshell cats are mostly female due to X inactivation, where one X chromosome in females becomes inactive, forming a Barr body. The process is described from the zygote stage, highlighting the randomness of which X chromosome is inactivated. The genetic basis of cat coloration, including epistasis, is explored. The podcast also touches on rare occurrences of X inactivation in humans, such as Klinefelter syndrome and disorders affecting sweat glands.

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3 questions

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1.

OPEN ENDED QUESTION

3 mins • 1 pt

Describe the process that leads to one X chromosome becoming inactive in female cells.

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2.

OPEN ENDED QUESTION

3 mins • 1 pt

What is epistasis and how does it relate to the coloration of calico cats?

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3.

OPEN ENDED QUESTION

3 mins • 1 pt

Can male cats be calico, and if so, under what circumstances?

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