Genetic Recombination and Gene Mapping

Mr. Andersen explains genetic recombination and gene mapping, focusing on Thomas Hunt Morgan's work with fruit flies. Morgan's experiments revealed that genes travel on chromosomes and undergo crossing over, leading to recombination. Despite expecting a 50% recombination rate, Morgan observed only 17%, prompting further investigation. Alfred Sturtevant discovered that genes on the same chromosome have lower recombination rates, leading to the concept of gene linkage. This understanding allowed for the creation of gene maps based on recombination frequencies. Today, DNA sequencing provides precise gene locations, validating Morgan and Sturtevant's findings.

What is the significance of Thomas Hunt Morgan's work with fruit flies in genetics?

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Explain the concept of crossing over in relation to genetic recombination.

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Describe the differences between parental phenotypes and recombinant phenotypes.

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How did Alfred Sturtevant contribute to the understanding of genetic recombination?

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Discuss the process of meiosis and its relevance to genetic recombination.

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What does a frequency of recombination of 17% imply about the genes on a chromosome?

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What modern techniques have replaced the methods used by Morgan and Sturtevant for gene mapping?

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