Phenylketonuria Enzymatic Pathways

The video discusses phenylketonuria, a condition caused by a deficiency in phenylalanine hydroxylase, leading to phenylalanine buildup. It explains how aspartame contributes to this buildup and the importance of food labels. The video also covers testing methods for phenylketonuria through urine analysis, highlighting the presence of phenyl pyruvate. Additionally, it explores alternative metabolic pathways for phenylalanine, including reactions with aminotransferase, reductase, and decarboxylase enzymes.

What is phenyl pyruvate and why is it significant in testing for phenylketonuria?

How does the concentration of phenylalanine affect the reaction involving aminotransferases?

What are the three products that are tested for in the urine of individuals suspected of having phenylketonuria?