Notch Signaling Pathway | Purpose and Mechanism

The video tutorial explains the notch signaling pathway, a crucial mechanism in cellular processes like proliferation, differentiation, and apoptosis. It describes the roles of notch receptors and ligands, the intercellular signaling mechanism, and the activation process involving mind bomb and ubiquitination. The tutorial covers the cleavage events leading to transcription of target genes and the pathway's downregulation. The lesson concludes with a call to action for viewer engagement.

What role does the protein Mindbomb play in the notch signaling pathway?

What happens to the notch intracellular domain after it is cleaved?

How is the expression of notch target genes regulated?