Gluconeogenesis Pathway: Overview, Enzymes, Co-Factors and Precursors

The video tutorial explains gluconeogenesis, the process of synthesizing glucose from non-carbohydrate precursors, crucial during fasting and starvation. It occurs mainly in the liver and kidneys. The tutorial compares gluconeogenesis with glycolysis, highlighting key enzymes and steps, including pyruvate carboxylase and PEP carboxykinase. It discusses the energy requirements, noting that gluconeogenesis consumes six ATP molecules. The regulation of the pathway by hormones like glucagon and the role of precursors such as lactate, amino acids, and glycerol are also covered.

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