Glycolysis and Gluconeogenesis Regulation 2

The video discusses the regulation of glycolysis and gluconeogenesis, focusing on the allosteric effects of fructose 2,6-bisphosphate. It explains how this molecule activates glycolysis by stimulating PFK-1 and inhibits gluconeogenesis by reducing the affinity of fructose bisphosphatase-1 for its substrate. The video emphasizes the importance of these regulatory mechanisms in metabolic pathways.

What happens to gluconeogenesis when fructose 2,6-bisphosphate is present?

How does the binding of fructose 2,6-bisphosphate to fructose bisphosphatase 1 affect its activity?