Pyruvate Carboxylase

The video tutorial explains the role of pyruvate carboxylase in gluconeogenesis, highlighting its mechanism involving biotin and lysine. It details the enzyme's dependence on cofactors like ATP and bicarbonate, and describes the two-step reaction process: generation of carbon dioxide and carboxylation of pyruvate to form oxaloacetate. The tutorial also discusses the unique tethering mechanism of biotin and compares similar enzymes in biochemistry.

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