NEW! Cytochrome c and Holocytochrome c Synthase: Biochemistry and Mechanism

NEW! Cytochrome c and Holocytochrome c Synthase: Biochemistry and Mechanism

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Science, Chemistry, Biology

University

Hard

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The video explores the role and synthesis of cytochrome C, a soluble protein in the mitochondria that transfers electrons between complexes 3 and 4. It details the structure of cytochrome C, focusing on the heme C prosthetic group and the conserved amino acid sequence required for its binding. The enzymatic mechanism of attaching cysteine residues to heme B, transforming it into heme C, is explained. The video also discusses the oxidation states of iron and their significance in electron transfer, concluding with a look at nucleophilic addition reactions involved in the process.

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3 questions

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1.

OPEN ENDED QUESTION

3 mins • 1 pt

Discuss the role of hollow cytochrome C synthase in the synthesis of cytochrome C.

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2.

OPEN ENDED QUESTION

3 mins • 1 pt

What is the importance of the oxidation state of iron in cytochrome C?

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3.

OPEN ENDED QUESTION

3 mins • 1 pt

How does cytochrome C interact with complex 3 and complex 4 in the electron transport chain?

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