Antibody Structure and Function

This video provides an overview of antibody structure, focusing on the Y-shaped proteins composed of heavy and light chains. It explains the variable region responsible for antigen binding and the constant region that determines the antibody class. The video discusses different antibody classes, such as IGM and IGG, and their roles in immune response. It also covers how antigen binding sites can be modified through hypermutation and genetic recombination, as well as the process of class switching, which allows antibodies to respond differently to the same antigen. The video concludes with a summary of antibody classes and their specific functions.

What is the basic shape of an antibody?

• X-shaped

• Y-shaped

• L-shaped

• Z-shaped

Which part of the antibody is responsible for binding to antigens?

• Heavy chain

• Variable region

• Constant region

• Light chain

What is the role of the constant region in an antibody?

• Binding to antigens

• Determining antibody class

• Mutating antigen sites

• Activating B cells

How can the antigen binding region of an antibody be modified?

• By changing the heavy chain

• Through hypermutation

• By altering the light chain

• Through class switching

What is the process called when an antibody switches from one class to another?

• Receptor editing

• Antigen binding

• Class switching

• Hypermutation

Which antibody class is secreted early in the primary immune response?

• IgG

• IgM

• IgE

• IgA

Which antibody class is most commonly found in the body?

• IgG

• IgA

• IgE

• IgM

Which antibody class is primarily involved in allergic reactions?

• IgA

• IgM

• IgE

• IgG

Where is IgA primarily found in the body?

• In the blood

• In the lymph nodes

• In the mucus membranes

• In the bone marrow

What cells produce antibodies after B cells are activated?

• T cells

• Dendritic cells

• Plasma cells

• Macrophages