
V(D)J Recombination and Immune Diversity
Interactive Video
•
Biology
•
11th - 12th Grade
•
Hard

Ethan Morris
FREE Resource
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10 questions
Show all answers
1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What are the two major types of lymphocytes involved in the adaptive immune system?
Dendritic cells and Basophils
Macrophages and Neutrophils
T cells and B cells
Eosinophils and Monocytes
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the primary purpose of V(D)J recombination in the immune system?
To destroy pathogens
To activate immune cells
To generate diverse antigen receptors
To produce antibodies
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which part of the immunoglobulin is encoded by VDJ gene rearrangements?
Light chain
Heavy chain
Variable region
Constant region
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the estimated number of possible Ig or TCR molecules?
1 million
10 million
100 million
1 billion
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What are recombination signal sequences (RSSs) composed of?
Heptamer and nonamer elements
Exons and introns
Codons and anticodons
Promoters and enhancers
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the 12/23 rule in V(D)J recombination?
Recombination occurs between two 12 base pair spacers
Recombination occurs between one 12 base pair spacer and one 23 base pair spacer
Recombination occurs between two 23 base pair spacers
Recombination occurs only in the presence of RAG1 and RAG2
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which enzymes are responsible for initiating DNA cleavage in V(D)J recombination?
Helicase
DNA polymerase
Ligase
RAG1 and RAG2
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