Dopachrome Tautomerase: Physiology, Biochemistry, and Mechanism

Dopachrome Tautomerase: Physiology, Biochemistry, and Mechanism

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Science, Biology, Chemistry

University

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The video explores the mechanism and physiology of the enzyme dopethrone tautomerase, also known as DOPA Chrome isomerase. It discusses the synthesis of melanin in melanocytes, focusing on the role of tyrosinase and DOPA Chrome tautomerase in converting DOPA to DOPA Chrome and further to dihydroxy indole carboxylic acid. The video explains the enzyme's structure, function, and the catalytic role of zinc cations and water molecules in the active site. The spontaneous and enzymatic pathways of the reaction are also covered.

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OPEN ENDED QUESTION

3 mins • 1 pt

What new insight or understanding did you gain from this video?

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