Glycogen Phosphorylase Function and Mechanism

The video explains the role of glycogen phosphorylase in breaking down glycogen into glucose-1-phosphate. It details the enzyme's mechanism, highlighting the formation of an oxonium species and the role of phosphate as a nucleophile. The video also discusses the conversion of glucose-1-phosphate to glucose-6-phosphate by phosphoglucomutase, preparing it for glycolysis. The importance of the enzyme's name, glycogen phosphorylase, is clarified, emphasizing its use of phosphate instead of water. The video concludes with a preview of the next topic on glycogen debranching enzymes.

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