Mechanism of X-Chromosome Aneuploidies [Klinefelter's, Turner's, & XXX]

The video explains the role of sex chromosomes in humans, focusing on the X and Y chromosomes. It discusses the concept of X chromosome inactivation and introduces three primary disorders caused by abnormal numbers of X chromosomes: Klinefelter syndrome, Turner syndrome, and Triple X syndrome. The video delves into the process of nondisjunction during oogenesis, which leads to these disorders, and uses Punnett squares to illustrate the resulting genotypes. It also covers the implications of these genotypes, including the presence of bar bodies and the Lyon hypothesis. The video concludes by emphasizing that these nondisjunction events are random and not heritable.

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