Nucleotide Metabolism | Degradation of IMP, AMP, & GMP

Nucleotide Metabolism | Degradation of IMP, AMP, & GMP

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Science, Biology, Chemistry

University

Hard

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The video explains the degradation pathways of purine nucleotides IMP, GMP, and AMP, focusing on their conversion to xanthine and eventually uric acid. It highlights the role of enzymes like 5 prime nucleotidase and xanthine oxidase in these processes. The absence of urate oxidase in humans is discussed, linking it to evolutionary advantages and the antioxidant role of uric acid. The video also touches on the implications of uric acid accumulation, such as gout.

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OPEN ENDED QUESTION

3 mins • 1 pt

What new insight or understanding did you gain from this video?

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