Wernicke’s Encephalopathy | Causes, Symptom Triad & Treatment

The video discusses Wernicke's Encephalopathy, an acute and reversible condition caused by a deficiency of vitamin B1 (thiamine). It highlights the common causes, such as chronic alcoholism and other conditions affecting nutritional absorption. The symptoms are summarized using the mnemonic 'CAN' for confusion, ataxia, and nystagmus. The pathophysiology involves thiamine's role in enzyme function, affecting energy metabolism. Treatment involves thiamine replacement, with a caution against administering glucose before thiamine. The video also warns about the potential development of Korsakoff syndrome if untreated.

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