ALA Synthase

The video explores the biosynthesis of heme, focusing on the synthesis of delta aminolevulinate, the committed step in heme production. It discusses the energetic costs of the process, the role of aminolevulinic acid synthase, and the regulation of heme synthesis through enzyme synthesis and allosteric inhibition by heme. The video also highlights the influence of barbiturates and steroids on enzyme activity, explaining why males have higher hemoglobin levels.

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