Ras Raf MEK ERK Signaling and the mTOR Pathway | Interactions and Regulation

The video explains the interaction between the Ras RAF MEK Erk and mtor pathways, focusing on how the Ras RAF MEK Erk pathway regulates mtor complex 1. It details the activation process of the Ras RAF MEK Erk pathway, its role in inhibiting TSC1 and TSC2, and the subsequent activation of mtor complex 1. The video also covers the downstream effects of mtor complex 1 activation, such as inhibition of autophagy and promotion of pyrimidine and protein synthesis. Additionally, it highlights the independent effects of the Ras RAF MEK Erk pathway on cell proliferation, survival, and metastasis.

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