Pyruvate Dehydrogenase

The video tutorial explains the TCA cycle, focusing on the conversion of pyruvate to acetyl CoA by the pyruvate dehydrogenase complex. It details the structure and function of this enzyme complex, its role in the TCA cycle, and its relation to other alpha ketoacid dehydrogenase complexes. The mechanism of pyruvate dehydrogenase is explored, highlighting the catalytic steps and regeneration of cofactors. The tutorial also discusses the functions of acetyl CoA in the TCA cycle and as a substrate for acetyl transferases in various biosynthetic pathways.

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