Lipid Biosynthesis Mechanism of Statins & Inhibiting CoQ Synthesis

The video explains the action of statin medications, which reduce cholesterol synthesis by inhibiting the enzyme HMG CoA reductase. It details the cholesterol biosynthesis pathway, highlighting the role of isoprenoids and Coenzyme Q. Statins lower cholesterol but also reduce Coenzyme Q and vitamin D synthesis, potentially affecting the electron transport chain. Supplementation with Coenzyme Q and vitamin D is advised for those on statins.

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