Biosignaling - G-protein-coupled Receptors PLC, DAG, & IP3

The video tutorial explains the G protein-coupled receptor pathways, focusing on the divergence from the adenylate cyclase pathway to the phospholipase C pathway. It details the signal transduction mechanism, the role of phospholipase C in hydrolyzing PIP2 into DAG and IP3, and the subsequent release of calcium ions from the endoplasmic reticulum. The activation of protein kinase C by DAG and calcium is discussed, leading to a phosphorylation cascade that results in a cellular response.

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