
Inositol Triphosphate (IP3) and Calcium Signaling Pathway | Second Messenger System
Interactive Video
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Health Sciences, Biology, Chemistry, Science
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University - Vocational training
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Hard
Wayground Content
FREE Resource
The video tutorial explains the IP3 pathway, detailing the roles of first and second messengers in cellular responses. It describes how extracellular ligands bind to G protein-coupled receptors, leading to the activation of phospholipase C, which cleaves PIP2 into IP3 and DAG. IP3 facilitates calcium release from the endoplasmic reticulum, while DAG and calcium activate protein kinase C, resulting in phosphorylation of target proteins and a cellular response.
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