Threonine and Methionine Catabolism to Succinyl CoA

The video explores the catabolism of methionine and threonine, detailing the enzymatic pathways involved. Methionine catabolism begins with methionine adenosyl transferase, leading to the production of homocysteine and further conversion to alpha-ketoglutarate. Threonine catabolism involves threonine dehydratase, producing alpha-keto butyrate. Both pathways converge at succinyl CoA, which plays a crucial role in the TCA cycle and gluconeogenesis. Methionine is glucogenic, while threonine is both ketogenic and glucogenic.

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