Methionine, Threonine Catabolism to Succinyl-S-CoA

The video tutorial explores the catabolism of methionine and threonine, focusing on their degradation pathways. Methionine catabolism involves enzymes like methionine adenosyl transferase and cystathionine beta synthase, leading to the production of alpha-ketobutyrate. Threonine catabolism involves threonine dehydratase, producing alpha-ketobutyrate as well. The conversion of propionyl CoA to succinyl CoA is detailed, highlighting its role in the TCA cycle and gluconeogenesis. Methionine is glucogenic, while threonine is both ketogenic and glucogenic.

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