Genetic Recombination and Gene Mapping

Mr. Andersen explains genetic recombination and gene mapping, focusing on Thomas Hunt Morgan's work with fruit flies. Morgan's experiments revealed that genes travel on chromosomes and undergo crossing over, leading to recombination. Despite expecting a 50% recombination rate, Morgan observed only 17%, prompting further investigation. Alfred Sturtevant discovered that genes on the same chromosome have lower recombination rates, leading to the concept of gene linkage. This understanding allowed for the creation of gene maps based on recombination frequencies. Today, DNA sequencing provides precise gene locations, validating Morgan and Sturtevant's findings.

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