Coagulation | The Intrinsic Pathway of Coagulation

The video tutorial explains the roles of high molecular weight kininogen and bradykinin in inflammation and vessel injury. It details the activation of the intrinsic pathway, highlighting the role of von Willebrand factor and platelets in clotting. The function of polyphosphate kinase in activating factor 12 is discussed, followed by an explanation of the coagulation cascade and the common pathway leading to thrombin formation. The importance of the extrinsic pathway in effective clotting is emphasized, with a comparison to the intrinsic pathway.

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