Understanding the PI3K/AKT/mTOR Pathway

What is the primary role of the PI3K/AKT/mTOR pathway in cells?

• To inhibit cell growth

• To promote cell cycle progression and survival

• To prevent cell proliferation

• To decrease protein synthesis

Which molecule is responsible for the initial activation in the PI3K pathway?

• mTOR

• AKT

• PI3K

• PIP3

How do receptor tyrosine kinases activate the PI3K pathway?

• Through dimerization and phosphorylation

• By binding to DNA

• Through lipid synthesis

• By inhibiting PIP2

What is one of the main effects of mTOR activation?

• Upregulation of translation and lipid synthesis

• Promotion of apoptosis

• Reduction of cell growth

• Inhibition of protein synthesis

What can result from the dysregulation of the mTOR pathway?

• Uncontrolled cell division leading to cancer

• Reduced protein synthesis

• Decreased cell survival

• Controlled cell division