Understanding rtPA and Its Uses in Critical Care

What is the primary function of rtPA in medical treatment?

• To reduce inflammation

• To lyse clots in emergent situations

• To enhance immune response

• To increase blood pressure

Which of the following is NOT a form of rtPA?

• Aspirin

• Tanectoplase

• Retivase

• Alteplase

How does rtPA primarily work to break down clots?

• By converting fibrinogen to fibrin

• By increasing platelet aggregation

• By reducing blood viscosity

• By catalyzing the conversion of plasminogen to plasmin

What is a common side effect of rtPA?

• Bleeding

• Hair loss

• Increased appetite

• Weight gain

Which serious adverse effect is associated with rtPA?

• Cerebral hemorrhage

• Liver failure

• Diabetes

• Kidney stones

For which condition is Alteplase specifically approved by the FDA?

• Acute ischemic stroke

• Chronic hypertension

• Diabetes

• Asthma

What is the preferred method of rtPA administration for myocardial infarction?

• Subcutaneous injection

• Accelerated infusion

• Oral tablet

• Topical application

In the case of massive pulmonary embolism, what is the recommended rtPA dose for hemodynamic compromise?

• 50 mg IV over 1 hour

• 100 mg IV over 2 hours

• 10 mg IV bolus

• 200 mg IV over 3 hours

What is the initial step in using rtPA to restore flow in an occluded central line?

• Perform a blood transfusion

• Infuse a 2 mg dose into the line

• Apply external pressure

• Administer a 10 ml flush

After how many minutes should you check the functionality of a central line after rtPA infusion?

• 30 minutes

• 10 minutes

• 60 minutes

• 90 minutes