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Amoeba Sisters: Nature of Science - Printable Science Worksheets 12th Grade - Wayground

Amoeba Sisters: Nature of Science

Krystal Covington

Created by Krystal Covington

1 questions

12th Grade

Science

Updated Sept 2026

Amoeba Sisters: Nature of Science is a free printable Grade 12 science worksheet that introduces foundational ideas about how science works and why it matters. Students complete one comprehension item and 10 multiple-choice questions covering the purpose of a science fair, the scientific method, control groups, graphing the independent variable on the X axis, and the collaborative nature of science. The worksheet also examines ethics, science communication, the goal of gaining knowledge, curiosity, and the meaning of the word “science.” These questions help students connect scientific investigation with evidence, comparison, credibility, communication, and discovery. Use the worksheet to review key vocabulary and concepts before a unit, check understanding after instruction, or prompt discussion about how scientists conduct and share their work. It includes a complete answer key for efficient checking and review.

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Amoeba Sisters: Nature of Science

Total questions: 1

Name
Class
Date
1-10.
1.

What is the purpose of a science fair?

a)

To sell science-related products

b)

To investigate a scientific problem

c)

To promote scientific theories

d)

To showcase scientific discoveries

2.

What is the scientific method?

a)

A model for developing scientific theories

b)

A method used only by certain scientists

c)

A recipe for making a cake

d)

A linear set of steps for conducting experiments

3.

What is the purpose of a control group in a scientific experiment?

a)

To validate the hypothesis

b)

To be excluded from the experiment

c)

To provide a baseline for comparison

d)

To receive the treatment being tested

4.

Where should the independent variable be placed on a graph?

a)

On the X axis

b)

On the Y axis

c)

On the Z axis

d)

On the W axis

5.

What is the nature of science?

a)

It is a global and collaborative effort

b)

It is a finished endeavor

c)

It is limited to certain branches

d)

It is only for experts

6.

What is the purpose of ethics in science?

a)

To ensure credibility of scientific findings

b)

To promote competition among scientists

c)

To limit scientific exploration

d)

To restrict access to scientific knowledge

7.

What is the role of science communication?

a)

To evaluate new scientific information

b)

To spread misinformation about science

c)

To limit access to scientific information

d)

To discourage curiosity about science

8.

What is the main goal of science?

a)

To restrict access to scientific knowledge

b)

To limit scientific exploration

c)

To promote scientific laws

d)

To gain knowledge

9.

What is the importance of curiosity in science?

a)

It can lead to new learning and discoveries

b)

It is irrelevant to scientific exploration

c)

It hinders the progress of science

d)

It is only for certain scientists

10.

What is the significance of the word 'science'?

a)

It means 'restricted access'

b)

It means 'limited knowledge'

c)

It means 'finished endeavor'

d)

It means 'knowledge'

WaygroundAnswer Key

Amoeba Sisters: Nature of Science

Total questions: 1

1-10.
1.
b)

To investigate a scientific problem

2.
d)

A linear set of steps for conducting experiments

3.
c)

To provide a baseline for comparison

4.
a)

On the X axis

5.
a)

It is a global and collaborative effort

6.
a)

To ensure credibility of scientific findings

7.
a)

To evaluate new scientific information

8.
d)

To gain knowledge

9.
a)

It can lead to new learning and discoveries

10.
d)

It means 'knowledge'

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FAQs

What does the Amoeba Sisters: Nature of Science worksheet cover?

This Grade 12 science worksheet uses one comprehension item and 10 multiple-choice questions to review foundational ideas about scientific investigation and the nature of science. Students identify the purpose of a science fair, the scientific method, the role of a control group, the placement of the independent variable on the X axis, and the importance of ethics, communication, curiosity, and knowledge. Completing these items helps students connect scientific practices with how evidence is investigated, compared, evaluated, and shared.

How can I use this worksheet to teach the nature of science?

Introduce the worksheet by asking students what makes an investigation scientific, then use the questions to build a sequence from investigation to communication. Pause after the science fair, scientific method, and control group items to have students explain how a scientific problem is investigated and how a baseline supports comparison. Follow with discussion of ethics, evaluating scientific information, curiosity, and collaboration so students see science as an ongoing, shared effort to gain knowledge.

What mistakes should I watch for when students complete this worksheet?

Students may confuse the purpose of a science fair with showcasing discoveries rather than investigating a scientific problem, or mistake the treatment group for the control group instead of recognizing the control as the baseline for comparison. They may also place the independent variable on the Y axis, overlook that ethics support the credibility of findings, or interpret science communication as simply spreading information rather than evaluating new scientific information. Review the reasoning behind each choice, not just the selected letter.

How do I assign and grade this Nature of Science worksheet?

Wayground provides this worksheet as both a printable PDF and a digital quiz, with a complete answer key for the one comprehension item and 10 multiple-choice questions. You can print copies for independent practice or review, or assign the digital version for online completion. Printable submissions can be graded by scanning student work with the Wayground for Teachers app.

How can I differentiate this Nature of Science worksheet for my students?

Use the worksheet’s Advanced Settings to adjust font spacing or increase the font size so the comprehension item and multiple-choice options are easier to read. You can also enable a dyslexia-friendly font or translate the worksheet into another language when appropriate. These changes preserve the focus on scientific investigation, control groups, ethics, and other nature-of-science concepts while changing the worksheet’s presentation.

Where can I find more worksheets like this on Wayground?

Wayground offers a broad collection of free printable worksheets and practice problems across subjects, with downloadable PDFs and answer keys to support essential skills and concepts. Browse more resources at https://wayground.com/en-us/worksheets.

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