WorksheetsMutation
Total questions: 25
Worksheet time: 1hrs 4mins
Name
Class
Date
1.
a change in the nucleotide sequence of DNA
a)
is a mutation
b)
can be a mutation or an epigenetic change
c)
is an epigenetic change
d)
always leads to a permanent change in DNA
2.
which of the following mutations results in the loss or addition of a single nucleotide, changing the DNA triplets
a)
missense
b)
nonsense
c)
frameshift
d)
silent
3.
What do mutations change?
a)
DNA
b)
Chromosomes
c)
Genes
4.
What mutation has occurred here?
T-G-A-C-C-A
T-G-A-G-C-A
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift
5.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.
a)
Substitution
b)
Deletion
c)
Insertion
d)
Inversion
6.
What type of chromosomal mutation is this?
a)
Inversion
b)
Translocation
c)
Deletion
d)
Duplication
7.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
8.
Gene: ABCDEF
Mutation: ACEFCD
What mutation occurred?
Mutation: ACEFCD
What mutation occurred?
a)
deletion
b)
substitution
c)
inversion
d)
insertion
9.
What are the building blocks of proteins called?
a)
DNA
b)
RNA
c)
Ribosomes
d)
Amino Acids
10.
In DNA, Adenine bonds with ______________.
a)
Guanine
b)
Thymine
c)
Cytosine
d)
Adenine
11.
Guanine bonds with ______________.
a)
Adenine
b)
Guanine
c)
Cytosine
d)
Thymine
12.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
a)
Substitution
b)
Insertion
c)
Inversion
d)
Translocation
13.
Which organelle is DNA usually found in?
a)
cell membrane
b)
vacuole
c)
chloroplast
d)
nucleus
14.
Why are insertion and deletion (frameshift) mutations so harmful?
a)
They change all of the codons from the mutation on down the line, which changes the amino acid sequence ultimately changing the protein.
b)
They insert things that an organism doesn't need.
c)
They often delete things that organisms need.
d)
Insertion and deletions are not any more harmful than substitution mutations.
15.
ATTTGAGCC- Original
ATTGAGCC - Mutated
The example above is an example of a
ATTGAGCC - Mutated
The example above is an example of a
a)
Insertion- Frameshift
b)
Deletion- Substitution
c)
Deletion -Frameshift
d)
All of the above
16.
Which RNA bases would pair with TACGAA in transcription?
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
17.
What causes mutations?
a)
Mistakes in replication or environmental influences
b)
The amino acids
c)
Passed down by genetics
d)
It's how your born
18.
Gene: ABCDEF
Mutation: ACEFCD
What mutation occurred?
Mutation: ACEFCD
What mutation occurred?
a)
deletion
b)
substitution
c)
inversion
d)
insertion
19.
What is the correct mRNA strand from this DNA?
CAC-GTG-ACA-GCG
CAC-GTG-ACA-GCG
a)
GTG-CAC-TGT-CGC
b)
CAC-GUG-ACA-GCG
c)
GUG-CAC-UGU-CGC
20.
Identify the mutation in the picture.
a)
Inversion
b)
Duplication
c)
Deletion
d)
Translocation
21.
If a mutation occurs in an expressed gene, it will most directly affect the structure of a cell's
a)
ATP
b)
proteins
c)
energy source
d)
membrane
22.
This diagram can be used to -
a)
translate codon into protein
b)
transcribe DNA into RNA
c)
duplicate DNA
d)
cell division
23.
illustration shows.
a)
sickle cell
b)
hemophilia
c)
turner's
d)
tay-sachs.
24.
Which of these is the correct order for the chromosome mutations in the image (from top to bottom)?
a)
(1) duplication, (2) inversion, (3) substitution, (4) translocation
b)
(1) deletion, (2) duplication, (3) inversion, (4) translocation
c)
(1) deletion, (2) insertion, (3) translocation, (4) inversio
d)
(1) substitution, (2) duplication, (3) translocation, (4) inversion
25.
the enzyme that is responsible for proofreading the addidion of nucleotides during replication and fixing any mistakes it finds
a)
repair system enzyme
b)
DNA polymerase
c)
RNA polymerase
d)
DNA mutase
100 %
