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#2. Mechanisms of Genetics

Total questions: 12

Worksheet time: 14mins

Name
Class
Date
1.

This part of the cell cycle is best described as the process that...

a)

duplicates the DNA

b)

completes cell division

c)

maintains genetic homeostasis

d)

synthesizes new molecules

2.

Differences in traits such as hair texture are determined by differences in -

a)

the location of sugar groups in DNA

b)

the sequence of nucleotides in DNA

c)

the number of nitrogenous bases in DNA

d)

the molecules attached to the phosphate in DNA

3.

Researches combined sequences of fruit-fly DNA from a gene for a particular trait with frog DNA. The mixture was heated to separate the DNA strands. Cooling allowed the single strands to form pairs. The researchers observed that some of the fruit-fly DNA paired with frog DNA.


The results provide evidence that...

a)

similar nucleotides are present in both fruit-fly and frog DNA

b)

fruit-flies and frogs can be made to develop some of the same physical traits

c)

heat can cause mutations in the DNA sequences of organisms

d)

the replication of genetic material can occur at any temperature

4.

In gel electrophoresis a DNA sample from an unknown donor is placed in a small well at one end of a special gel-coated plate. Samples from known donors are placed in other wells on the plate. An electric current is passed through the plate, causing the DNA fragments to separate. The size and location of the separated fragments can be compared for similarities. The more similar the locations and sizes of the fragments, the more closely the donors of the samples are related. The diagram shows four samples being compared with an unknown sample.


The donor of which sample is most closely related to the donor of the unknown sample?

a)

Sample 1

b)

Sample 2

c)

Sample 3

d)

Sample 4

5.

In Holstein cattle the allele for black hair (B) is dominant over the allele for red hair color (b), and the allele for polled (P), or lacking horns, is dominant over the allele for having horns (p).


What is the expected phenotypic ratio of the offspring of a BbPp x BbPp cross if these alleles sort independently?

a)

16 black/polled : 0 black/horned : 0 red/polled : 0 red/horned

b)

12 black/polled : 0 black/horned : 0 red/polled : 4 red/horned

c)

4 black/polled : 4 black/horned : 4 red/polled : 4 red/horned

d)

9 black/polled : 3 black/horned : 3 red/polled : 1 red/horned

6.

People who have leukemia, a cancer that affects white blood cells, are often given Cytarabine. This drug inhibits the synthesis of DNA. Which phase of the cell cycle is most affected by Cytarabine?

a)

G1phase

b)

S phase

c)

G2 phase

d)

M phase

7.

In the early 1900s a scientist hypothesized a link between DNA and the production of proteins in the cytoplasm. However, the fact that DNA could not be found outside the nucleus led scientists to believe that another substance was also involved in the synthesis of protein in the cytoplasm. In the 1940s scientists performed an experiment that ultimately identified the site of protein synthesis. They also identified the molecule responsible for transporting information from the nucleus to the site of protein synthesis. What was this newly identified molecule?

a)

a gene

b)

mRNA

c)

ATP

d)

Thyamine

8.

During meiosis, homologous chromosomes exchange genetic material. This exchange of genetic material —

a)

increases the genetic variation

b)

reduces the diploid number to the haploid number

c)

increases the haploid number to the diploid number

d)

reduces the probability of mutations

9.

The initial steps in gene expression are modeled below. Double-stranded DNA first unwinds into two strands


Which process and product are represented in Diagram 2?

a)

Process: transcription; product: mRNA

b)

Process: translation; product: protein

c)

Process: replication; product: tRNA

d)

Process: recombination; product: polymerase

10.

Each strand of a DNA molecule contains nitrogenous bases that pair with other nitrogenous bases in very specific ways. A diagram of a section of DNA is shown.


Which DNA strand is complementary to the one shown above?

a)
b)
c)
d)
11.

Oncogenes are mutated forms of genes. Oncogenes can transform a cell into a tumor cell. Some tumor cells are benign, while others are malignant. How does the presence of an oncogene lead to the formation of a tumor?

a)

ATP production is inhibited.

b)

Cell division is unregulated.

c)

Somatic cell growth is inhibited.

d)

Antibody activity is unregulated.

12.

The table shows a DNA sequence and three types of mutations that can change the DNA sequence.


Which mutation will cause translation to stop?

a)

Mutations 1 and 3 only

b)

Mutation 1 only

c)

Mutation 2 only

d)

Mutations 1, 2, and 3