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IRP Quiz (H)

Total questions: 35

Worksheet time: 18mins

Name
Class
Date
1.

Rod-shaped cells are called:

a)

cocci

b)

bacilli

c)

spirochetes

d)

viruses

2.

Spherical bacteria are called:

a)

cocci

b)

bacilli

c)

spirochetes

d)

viruses

3.

Which one of the following statements about gram-positive and gram-negative bacteria is true?

a)

Gram-positive are spirochetes and gram-negative bacteria are cocci

b)

Gram-negative bacteria have a thicker peptidoglycan layer than gram-positive bacteria

c)

Gram-positive bacteria have a plasma membrane and gram-negative bacteria do not

d)

Gram-negative bacteria have an outer membrane and gram-positive bacteria do not

4.

Gram-positive bacteria:

a)

turn purple when stained with crystal violet

b)

turn pink when stained with crystal violet

c)

are not able to absorb crystal violet

d)

are only able to absorb crystal violet if it's deionized

5.

What is LB agar?

a)

A nutritionally enriched medium made of seaweed

b)

A gelatinous substance that can be used to grow bacteria

c)

A food source for bacteria

d)

All of the above

6.

How would you classify the bacteria shown here?

a)

Gram-positive

b)

Gram-negative

c)

Inconclusive

d)

Spirochete

7.

What form of reproduction do bacteria use?

a)

Asexual reproduction (mitosis)

b)

Asexual reproduction (meiosis)

c)

Sexual reproduction (mitosis)

d)

Sexual reproduction (meiosis)

8.

What can be seen on the agar plate below?

a)

Individual bacterial cells

b)

Gram-positive bacteria

c)

Bacterial colonies

d)

Egg cells being fertilized

9.

About how long does it take for bacteria to replicate?

a)

20 hrs

b)

20 min

c)

20 sec

d)

20 days

10.

Which one of the following processes must come FIRST for gram-staining?

a)

Cover slide with crystal violet for 1 min

b)

Suspend bacterial colony in water on microscope slide

c)

Rinse slide with ethanol

d)

Look at bacteria under microscope

11.

Which step of DNA sequencing comes comes first?

a)

Growing bacteria in a liquid culture (liquid agar)

b)

PCR (Polymerase Chain Reaction)

c)

Gel Electrophoresis

d)

Sending out samples to GeneWiz to be sequenced

12.

What is the goal of making a liquid culture of bacteria?

a)

To replicate the 16S ribosomal subunit so we can have enough samples to send out and sequence

b)

To make sure we have replicated the correct gene

c)

To send it directly to Genewiz to be sequenced

d)

To begin to break apart the bacterial colonies into cells and begin to multiply

13.

What is the goal of PCR?

a)

To make sure we have replicated the correct gene

b)

To amplify (make millions of copies of) a specific gene

c)

To transfer bacterial colonies from the petri dishes to a liquid medium so that they can break apart into cells & begin to multiply

d)

To break down the cells into DNA so that they can be replicated

14.

What is the goal of gel electrophoresis?

a)

To make sure the correct gene sequence has been copied

b)

To amplify (make millions of copies of) a specific gene

c)

To transfer bacterial colonies from a petri dish to a liquid medium so they can break apart into cells & begin to multiply

d)

To break down the cells into DNA so they can be replicated

15.

What does PCR stand for?

a)

Polynucleotide Chain Reaction

b)

Polysaccharide Carbohydrate Redundancy

c)

Polymerase Culture Reaction

d)

Polymerase Chain Reaction

16.

What is the purpose of placing the liquid culture Eppendorf tubes into a thermomixer?

a)

To replicate millions of copies of the bacterial DNA

b)

To break down the colonies into cells so they may begin to multiply

c)

To mix several types of bacterial DNA together into one solution

d)

To make sure that the 16S Ribosomal subunit has been copied correctly

17.

What is the function of a thermocycler?

a)

It aerates the liquid cultures in order to break apart bacterial cells into colonies, so they may begin to multiply

b)

It's used during PCR to replicate the bacterial cells

c)

It's used during PCR to replicate a specific gene sequence into millions of copies

d)

It uses electrodes and a gel in order to separate DNA fragments

18.

What are the correct components of the "Master Mix" that we used throughout PCR in order to replicate the 16S ribosomal subunit?

a)

DNA polymerase, Nitrogen bases, Sterilized water, & Primers

b)

DNA polymerase, Primers, Iodine, Starch, & Sterilized water

c)

RNA polymerase, Nitrogen bases, Sterilized water, & Primers

d)

Primers, Loading dye, Ladder, & Sterilized water

19.

How much of the liquid culture did we add to the PCR tubes that were pre-filled with master mix?

a)

20ul

b)

2ul

c)

48ul

d)

10ul

20.

What is the correct order of events (of replication) that occur during PCR?

a)

Denaturation, Extension, Annealing

b)

Annealing, Extension, Denaturation

c)

Thermocycling, Denaturation, Extension

d)

Denaturation, Annealing, Extension

21.

What occurs during the "denaturation" stage of PCR?

a)

Primers attach to the DNA template

b)

DNA is unwound/unzipped

c)

Nucleotides are added onto the growing DNA strand

d)

Bacterial cells are broken down so the DNA can be accessed

22.

What occurs during the "Annealing" stage of PCR?

a)

Primers attach to the DNA template

b)

Nucleotides are added onto the growing DNA strande

c)

DNA is unwound/unzipped

d)

Bacterial cells are broken down so the DNA can be accessed

23.

What occurs during the "Extension" stage of PCR?

a)

Primers attach to the DNA template

b)

Nucleotides are added onto the growing DNA strand

c)

Bacterial cells are broken down so the DNA can be accessed

d)

DNA is unwound/unzipped

24.

What 2 liquids were combined and placed into the wells of the gels during gel electrophoresis?

a)

Ladder + Loading dye

b)

Sterilized water + Loading dye

c)

Ladder + Sterilized water

d)

PCR product + Loading dye

25.

Which one of the following statements about gel electrophoresis is TRUE?

a)

Positively charged DNA moves towards the negative electrode of a gel

b)

The larger DNA fragments travel farther through the gel than the smaller DNA fragments

c)

Negatively charged DNA moves towards the positive electrode of a gel

d)

As the DNA travels through the gel, it's able to multiply and make millions of copies

26.

Approximately how large is the 16S ribosomal subunit gene?

a)

300 base pairs

b)

750 base pairs

c)

900 base pairs

d)

1500 base pairs

27.

Which company is going to be sequencing our DNA for us?

a)

Cambridge Analytica

b)

GeneWiz

c)

MIT Analytics

d)

Complete Genomics

28.

Which one of the following components does NOT need to be included in your final lab reports?

a)

Abstract

b)

Results

c)

Sources of Error

d)

Sequencing

29.

Which one of the following statements about your IRP lab report is FALSE?

a)

All raw data should be included in the results section

b)

Each data table & graph should have a detailed title

c)

Each data table & graph should have a descriptive paragraph written underneath it

d)

Your hypothesis should be included within the introduction

30.

Which option below is an example of quantitative data?

a)

57% increase in bacterial colony growth

b)

Small, white, translucent bacterial colonies

c)

Gram-positive bacteria

31.

Which one of the following options includes information that should NOT be in your discussion section of your IRP lab writeup?

a)

Whether or not your hypothesis was supported or refuted

b)

Sources of error

c)

Explanations with supporting background research

d)

Graphs and Data tables

32.

What is the correct option for listing the name of a specific bacteria?

a)

Streptococcus epidermidis

b)

Streptococcus Epidermidis

c)

Streptococcus epidermidis

d)

Streptococcus Epidermidis

33.

What is the correct protocol for discarding used petri dishes?

a)

Fill them with sterilized water and discard in the trash

b)

Cover the agar/bacteria with a 10% bleach solution & allow to sit for 20 minutes before discarding in trash

c)

Cover petri dishes, discard in a trash can, and spray with bleach

d)

Scrape agar/bacteria out of petri dish with a gloved hand and discard in trash

34.

At what temperature were your petri dishes incubated at, in order to ensure bacterial replication?

a)

72 F

b)

12 C

c)

32 F

d)

37 C

35.

Which one of the following statements is TRUE?

a)

All petri dishes must be stored in the incubator agar side up, but in the fridge they must be stored agar side down

b)

Petri dishes must be stored agar side up at all times

c)

As long as there is no condensation inside the petri dishes, they can be stored agar side down

d)

The covers of the petri dishes must be removed before placing them into the incubator