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PLRC1&2:yr2018

Total questions: 20

Worksheet time: 15mins

Name
Class
Date
1.

Paracortical hyperplasia is an expansion of ...

a)

B cells

b)

T cells

c)

histiocytes

d)

plasma cells

e)

follicular dendritic cells

2.

Which of the following entities is categorized into follicular hyperplasia group?

a)

Kikuchi-Fujimoto disease

b)

Luetic lymphadenitis

c)

Rosai-Dorfman disease

d)

Sinus histiocytosis

e)

Cat-scratch disease

3.

Which of the following is pan B-cell marker?

a)

CD3

b)

CD7

c)

CD20

d)

CD34

e)

CD68

4.

Which of the following is the marker of immaturity (blast marker)?

a)

CD3

b)

CD20

c)

CD34

d)

CD68

e)

Myeloperoxidase

5.

Which of the following is the histiocytic marker?

a)

CD3

b)

CD7

c)

CD20

d)

CD68

e)

CD34

6.

According to WHO classification, which of the following parameters is NOT use for classifying hematopoietic and lymphoid neoplasms?

a)

clinical parameter

b)

genetic parameter

c)

morphologic parameter

d)

social status parameter

e)

immunophenotypic parameter

7.

Which of the following is categorized into precursor lymphoid neoplasm group?

a)

angioimmunoblastic lymphoma

b)

anaplastic large cell lymphoma

c)

diffuse large B-cell lymphoma

d)

T prolymphocytic leukemia

e)

T lymphoblastic leukemia/lymphoma

8.

Which of the following is an indolent B-cell neoplasm?

a)

follicular lymphoma

b)

diffuse large B-cell lymphoma

c)

B lymphoblastic leukemia

d)

Burkitt lymphoma

9.

Hodgkin lymphoma is a group of...

a)

precursor B-cell neoplasm

b)

precursor T-cell neoplasm

c)

mature B-cell neoplasm

d)

mature T-cell neoplasm

10.

Which of the following is NOT categorized into classical Hodgkin lymphoma group?

a)

mixed-cellularity Hodgkin lymphoma

b)

nodular-sclerosis Hodgkin lymphoma

c)

lymphocyte-rich Hodgkin lymphoma

d)

lymphocyte-depleted Hodgkin lymphoma

e)

nodular lymphocyte predominant Hodgkin lymphoma

11.

A large cell with angulated vesicular nucleus, distinct nucleolus, and friable foamy cytoplasm is found in a newly diagnosed classical Hodgkin lymphoma patient. What is the name of this cell?

a)

popcorn cell

b)

lacunar cell

c)

mummified cell

d)

mononuclear cell variant

12.

Hodgkin & Reed-Sternberg cells found in classical Hodgkin lymphoma usually express...

a)

CD3

b)

CD20

c)

CD30

d)

CD34

e)

CD45

13.

Follicular center cells (cells in germinal centers) are usually negative to...

a)

CD10

b)

CD20

c)

BCL6

d)

BCL2

e)

Ki-67

14.

Which of the following condition is not categorized into myeloproliferative neoplasm group?

a)

polycythemia vera

b)

primary myelofibrosis

c)

myelodysplasia

d)

essential thrombocythemia

15.

Tumor of thymocytes is...

a)

thymoma

b)

T lymphoblastic lymphoma

c)

T prolymphocytic leukemia

d)

diffuse large B-cell lymphoma

16.

Which of the following is NOT the feature found in patients with hypersplenism?

a)

pancytopenia

b)

splenomegaly

c)

marrow hypocellularity

d)

clinical improvement after splenectomy

17.

Splenic lymphoma usually involves...

a)

red pulp

b)

white pulp

c)

splenic trabeculae

d)

splenic vessels

18.

The following conditions could cause congestive splenomegaly EXCEPT

a)

liver fibrosis (cirrhosis)

b)

splenic vein thrombosis

c)

Budd-Chiari syndrome

d)

thrombosis of celiac trunk

19.

Philadelphia chromosome is on...

a)

chromosome 8

b)

chromosome 9

c)

chromosome 21

d)

chromosome 22

20.

JAK2 V617F mutation could be found in these conditions EXCEPT

a)

polycythemia vera

b)

essential thrombocythemia

c)

primary myelofibrosis

d)

chronic myelogenous leukemia