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Genomic Analysis

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Genomics is the study of genomes. Genome refers to

a)

DNA of an organism

b)

Total DNA and RNA of an organism

c)

Entire genes of an organism

d)

Total DNA, RNA and cDNA of an organism

2.

Variation between individual due to single base change is called as

a)

ESTs

b)

SNPs

c)

contigs

d)

Transversion

3.

CpG island are

a)

Areas in genome which are rich in C and G

b)

Clusters of C with scattered G

c)

Clusters of C with scattered G

d)

All of these

4.

Which one of the following types of mutation is most likely to lead to premature termination of translation?

a)

Insertion of a single base into DNA

b)

Deletion of three bases from DNA

c)

Deletion of an entire gene

d)

Exon skip

5.

A map unit refers to

a)

The relative distance between genes on a chromosome

b)

The chromosomes that exchange parts during meiosis

c)

The percentage of recombination

d)

(1) and (3)

6.

Which of the following mechanism generate repetitive DNA?

a)

Transposition

b)

Deletion

c)

Duplication

d)

(1) and (3)

7.

Which of the following is correct regarding genomics?

a)

It include genome sequencing

b)

It include mapping of genome

c)

It include genome analysis

d)

All of these

8.

Genome annotation is the process of identifying ....

a)

The location of genes

b)

The coding regions

c)

Regulatory sequences

d)

All of these

9.

SNPs are formed as a result of

a)

Deletion

b)

Duplication

c)

Point mutation

d)

All of these

10.

QTL stands for

a)

Quality trait loci

b)

Query trait loci

c)

Quantitative trait loci

d)

None of these

11.

Which one of these are exclude of our 'other' genomes?

a)

Mitochondrial

b)

Chloroplast

c)

Metagenome

d)

Epigenome

12.

What are the intergenic regions in the genome?

a)

Repetitive DNA

b)

Endogenous retroviruses

c)

Pseudogenes

d)

All of these

13.

Which one of these are incorrect relation between DNA and genes?

a)

The primary DNA sequence encodes all the gene products necessary for an organism.

b)

The primary DNA sequence also includes a large number of regulatory signals.

c)

Much of the DNA sequence does not have an assigned function as of yet.

d)

One primary DNA sequence encode only a gene product for an organism.

14.

SNPs can end up anywhere in the genome. What incorrect effect they can have to the gene?

a)

no amino acid change

b)

amino acid change

c)

stop kodon

d)

protein expansion

15.

What are the types of DNA found in a eukaryotic genome?

a)

Highly repetitive

b)

Moderately repetitive

c)

Single/low copy

d)

All of these