WorksheetsSERUM INDICES: MANAGING ASSAY INTERFERENCE
Total questions: 10
Worksheet time: 6mins
Which of the following analytical phase in clinical laboratory testing produce the highest frequency of errors?
Analytical Phase
Post-Analytical Phase
Pre-Analytical Phase
The sources of endogenous interference include the following substances EXCEPT?
Bilirubin
Drugs
Hemoglobin
Lipids
Hemolysis is defined as breakdown of Leukocytes in blood which release hemoglobin & intracellular contents from cells. TRUE or FALSE ?
TRUE
FALSE
Which of the following is NOT mechanism of haemolysis interference?
Chemical reaction of heme or its iron with reagent components
Falsely increase in analytes concentration released from intracellular.
Light scattering effect due to large size of lipoproteins or particulate matter
Spectral interference of Hemoglobin at 340-440 nm & 540-580 nm.
''The yellowish serum or plasma colour resulting from increased sample bilirubin concentration. ''
The above statement show the definition of ?
Hemolysis
Lipaemic
Icterus
The following factors contribute to in vitro haemolysis in blood sample EXCEPT?
Traumatic collection
Errors in sample handling
Inherited hemolytic anemia
Collection of blood
The following answers show the strengths of automated measurement of serum indices.
Consistent than human visual
Less Accurate compare to human visual
Increase Laboratory Turn Around Time (LTAT)
Enhanced accuracy of reportable test results.
What kind of interference present in this sample?
Icteric
Lipaemic/Turbidity
Hemolysis
Choose the correct cause(s) of Lipaemic sample.
Recent fatty meal
Diabetes mellitus
Medication
High cholesterol intake
Among these interference substances, which is the common pre-analytical error affecting biochemistry results?
Lipamia
Hemolysis
Icterus
