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Foundations Week 2

Total questions: 18

Worksheet time: 18mins

Name
Class
Date
1.

What is true regarding the region indicated in green vs the lighter pigmented region?

a)

More T cells

b)

More dendritic cells

c)

More epithelial cells

d)

More macrophages

e)

More Hassall's corpuscles

2.

Which of the following is true regarding lymph tissue and lymphatic vessels?

a)

Thymocytes are derived from thymic progenitor cells

b)

DCs and antigens enter lymph nodes via efferent vessels

c)

Peyer's patches contain B, T, and dendritic cells

d)

Lymphatic ducts are valveless

e)

Lymphatics and blood stream are independent

3.

Which of the following amino acids is only ketogenic?

a)

Methionine

b)

Tryptophan

c)

Isoleucine

d)

Leucine

e)

Phenylalanine

4.

The precursor of serotonin could best be described as:

a)

Aromatic

b)

Nonpolar

c)

Aliphatic

d)

Charged

e)

Sulfur containing

5.

It's exam time and you're drenched in sweat because you were binge streaming The Boys instead of studying. Which of the following is true regarding signaling to your sweat glands right now?

a)

Increased preganglionic stimulation at muscarinic receptors

b)

Increased preganglionic stimulation at adrenergic receptors

c)

Increased postganglionic stimulation at muscarinic receptors

d)

Increased postganglionic stimulation at nicotinergic receptors

e)

Increased postganglionic stimulation at adrenergic receptors

6.

NE binds an alpha 1 receptor coupled to Gq, what happens?

a)

Increased adenylyl cyclase

b)

Decreased adenylyl cyclase

c)

Increased cyclic AMP

d)

Decreased protein kinase C

e)

Increased IP3

7.

The epitope in green will be recognized by:

a)

Antibodies

b)

B cell receptors

c)

T cell receptors

d)

Innate receptors

e)

All of the above recognize

8.

Which of the following is only immunogenic when linked to a carrier?

a)

Immunogens

b)

Haptens

c)

Tolerogen

d)

Mitogen

e)

Adjuvant

9.

Subjecting a protein to extreme heat will most likely reduce it to a structure that:

a)

Is held by hydrogen bonds in the polypeptide backbone

b)

Is a unique sequence of AA in a polypeptide chain

c)

Has a pattern of secondary structural elements in 3D conformation

d)

Is composed of individual polypeptides in a stoichiometric arrangement

e)

Is a structure composed of alpha helixes and beta sheets

10.

An immunoglobulin is an example of what protein structure?

a)

Primary

b)

Secondary

c)

Tertiary

d)

Quaternary

11.

Infant presents with failure to thrive, erythroderma, diarrhea, and markedly decreased B and T cells. This is most likely due to?

a)

Absence of RAG

b)

Decreased VDJ recombination

c)

Limited variability of Fc region

d)

Over-expression of a single Ig isotype

e)

Decreased junctional diversity

12.

Which of the following monomers has both opsonization and complement activation functions?

a)

IgA

b)

IgD

c)

IgG

d)

IgE

e)

IgM

13.

What type of inhibitor is represented by the red line?

a)

Noncompetitive

b)

Competitive

c)

Irreversible

d)

Allosteric

e)

Uncompetitive

14.

Which of the following catalyzes the formation of C bonds w/ O, S, or N?

a)

Oxidoreductase

b)

Transferase

c)

Hydrolases

d)

Lyases

e)

Ligases

15.

A pt w/ deficiency of complement C4 would most likely still be able to activate which of the following?

a)

Alternative pathway

b)

Classical pathway

c)

Lectin pathway

d)

All of the above

16.

Which of the following acts in an autocrine fashion to activate NK cell?

a)

TNFalpha

b)

IFNalpha

c)

IFNBeta

d)

IFNgamma

e)

IL-12

17.

This lipid composed of an ABCD 4 member ring system comprises ~30% of animal cell membranes and is the precursor for bile salt:

a)

Sphingolipid

b)

Phospholipid

c)

Cholesterol

d)

Cholesterol ester

e)

Sterol

18.

Which of the following is a phosphosphingolipid?

a)

Sphingomyelin

b)

Ganglioside

c)

Cerebroside

d)

Globoside

e)

Sulfatide