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RECOMBINANT DNA TECHNOLOGY

Total questions: 20

Worksheet time: 15mins

Name
Class
Date
1.
Which is true about plasmids?
a)
Plasmids can be cut at specific sequences called restriction sites.
b)
Plasmids contain a promoter sequence that defines where transcription begins.
c)
Plasmids can contain an antibiotic resistance gene.
d)
All of the statements are true about plasmids.
2.
In bacteria, restriction enzymes are used for defense. They cut up the DNA of a virus that infects bacteria.
a)
True
b)
False
3.

Which of the following terms describes the process of the uptake of recombinant plasmids into bacteria cells?

a)

amplification

b)

insertion

c)

transformation

d)

screening

4.

Which enzyme helps fuse the foreign into the new DNA?

a)

DNA Polymerase

b)

DNA ligase

5.

The cell that able to receive recombinant DNA for cloning purpose known as

a)

vector

b)

target DNA

c)

plasmid

d)

host cell

6.

To produce desired protein _____________ should be taken from any source like human, animal and plant.

a)

recombinant DNA

b)

Target DNA

c)

plasmid

d)

ligase

7.

Bacteria use restriction enzymes to protect themselves from:

a)

other bacteria

b)

plants

c)

antibiotics

d)

viruses

8.

Which of the following enzymes can cut nucleic acids?

a)

DNA polymerase

b)

restriction endonuclease

c)

modifying enzymes

d)

reverse transcriptase

9.

Which restriction enzyme listed below was isolated from E. coli bacteria?

a)

EcoRI

b)

HindIII

c)

HaeII

d)

SmaI

10.

Which of the following is NOT a tool used in genetic engineering?

a)

plasmid

b)

restriction enzyme

c)

DNA helicase

d)

DNA ligase

11.

What type of cut is this photo?

a)

Blunt

b)

sticky

12.

During insertion step,

a)

The recombinant plasmid is inserted into a host cell

b)

The gene of interest is inserted into a plasmid

c)

The plasmid is inserted into the gene of interest

13.

From where does Taq polymerase come?

a)

Bacteria that live in hydrothermal vents/hot springs.

b)

Cambodia

c)

The rain forest

14.

What happens in the Denature step of PCR?

a)

The DNA nucleotides are broken apart.

b)

The base-pairing rules for DNA are reversed.

c)

The double-stranded DNA is separated into two single strands of DNA.

15.

At what temperature does the denaturation step of PCR occur?

a)

95° C

b)

50° C

c)

72° C

16.

At what temperature does the Extension step of PCR occur?

a)

95°C

b)

50-65°C

c)

72°C

17.
What happens during the Anneal step of PCR?
a)
Primers are created.
b)
The primers attach to the target DNA region.
c)
Primers copy the new DNA strand.
d)
Primers sequence DNA
18.
Which of the following best describes the role of primers?
a)
Frame the beginning and end of the target sequence
b)
Copy the DNA 
c)
Cause DNA strands to separate
d)
Heat the sample
19.

If two double-stranded DNA molecules are used at the beginning of a polymerase chain reaction (PCR) process, how many double-stranded DNA molecules can be obtained after two cycles?

a)

2

b)

4

c)

8

d)

32

20.
T6- What type of macromolecule are restriction enzymes?
a)
nucleic acid
b)
carbohydrate
c)
protein
d)
lipid