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Cell cycle and cancer

Total questions: 48

Worksheet time: 1hrs 1mins

Name
Class
Date
1.
The causes of cancer may include which of the following?
a)
environmental influences
b)
UV radiation
c)
viruses
d)
all of these
2.
Which of the following explains why a cell's size is limited?
a)
a. volume increases faster than surface area
b)
b. surface area increases faster than volume
c)
c. homeostasis is disrupted by a cell that is too large
d)
d. both a and c are correct
3.
Among the following, the term that includes the others is ___.
a)
interphase
b)
nuclear division
c)
mitosis
d)
cell cycle
4.
The longest phase of the cell cycle 
a)
prophase
b)
interphase
c)
metaphase
d)
mitosis
5.
A chromatid is attached to a spindle fiber by the
a)
nucleolus
b)
deep furrow
c)
centromere
d)
centriole
6.
Identify the phase of mitosis
a)
prophase
b)
metaphase
c)
anaphase
d)
telophase
7.
The structures that hold together sister chromatids
a)
tissues
b)
chromosomes
c)
spindle
d)
centromeres
8.
The process by which the nuclear material is divided equally between two new cells
a)
mitosis
b)
cancer
c)
spindle
d)
centromere
9.
The dark staining structures that carry the genetic material 
a)
centromeres
b)
chromosomes
c)
tissues
d)
sister chromatids
10.
the uncontrolled division of cells that results in malignant growth 
a)
tissues
b)
cancer
c)
mitosis
d)
anaphase
11.
the two halves of the doubled chromosome structure 
a)
centromeres
b)
sister chromatids
c)
spindle
d)
tissues
12.
the sequence of growth and division of a cell
a)
cell cycle
b)
mitosis
c)
anaphase
d)
cancer
13.
the phase of mitosis in which the sister chromatids separate from each other
a)
prophase
b)
metaphase
c)
anaphase
d)
telophase
14.
sequence
a)
C,D, B, A, F, E
b)
D,A,F,C,E,B
c)
B,E,C,F,A,D
d)
C,B,D,A E,F
15.
Which is Metaphase?
a)
A
b)
E
c)
C
d)
F
16.

Most prokaryotic organisms reproduce mainly by the process of

a)

regeneration

b)

binary fission

c)

budding

d)

production of spores

17.

When a eukaryotic cell is not dividing, its genetic material can be found in the form of very long thin fibers called

a)

chromatin

b)

chromosomes

c)

the nucleolus

d)

RNA

18.

During prophase of mitosis, each chromosome of a eukaryotic cell consists of a pair of identical structures called

a)

chromatid

b)

sister chromosomes

c)

DNA transcript

d)

sister chromatids

19.

The process by which the cytoplasm of a eukaryotic cell divides to produce two cells is called

a)

mitosis

b)

cytokinesis

c)

binary fission

d)

telophase

20.

Which of the following occurs during mitotic anaphase?

a)

centromeres of each chromatid divide

b)

sister chromatids separate

c)

daughter chromosmes begin to move towards opposite poles of the cell

d)

all of the above

21.

During which phase of mitosis do the chromosomes line up on a plane located equidistant from the two spindle poles?

a)

interphase

b)

prophase

c)

metaphase

d)

anaphase

22.

During which phase of mitosis does the nuclear envelope reform and the nucleoli reappear?

a)

interphase

b)

prophase

c)

metaphase

d)

telophase

23.

Which of the following is a feature of a plant cell division that distinguishes it from an animal cell dividing?

a)

a cell plate forms

b)

a cleavage furrow forms

c)

cytokinesis does not occur

d)

four new cells are present

24.

Which of the following is likely to account for the differences between plant cell and animal cell cytokinesis?

a)

plant cells lack microfilaments needed for cleavage furrow

b)

animal cells lack chloroplasts

c)

plant cell division must maintain the integrity of the cell wall

d)

plant and animal cells do not have a common ancestor

25.

The cell cycle control system

a)

receives messages from the outside of the cell that influence cell division

b)

triggers and controls major events in the cell cycle

c)

is influenced by growth factors that bind to cell receptors

d)

all of the above

26.

Which of the following occurs during interphase?

a)

growth of the aster

b)

duplication of chromosomes

c)

cell growth

27.

Which of the following is NOT a function of mitosis in humans?

a)

repair of wounds

b)

growth

c)

production of reproductive cells

d)

multiplication of body cells

28.
Cancer creates abnormal cells by disrupting
a)
the cell cycle
b)
red blood cell formation
c)
DNA replication
d)
ATP synthesis
29.
Any substance that is known to cause cancer is called a
a)
carcinogen
b)
nicolyte
c)
pathogen
d)
retrovirus
30.
Metastasis is
a)
the spread of cancer from one part of the body to another.
b)
the growth of tumors in the lungs
c)
cancer of the blood cells
d)
cancer that is found in connective tissues
31.
Using drugs or medicines to destroy cancer cells.
a)
chemotherapy
b)
radiation therapy
c)
cancer surgery
d)
mitotic spindling
32.
An abnormal mass of cancer cells is called a 
a)
tumor
b)
cyst
c)
lesion
d)
polyp
33.
Which of these  is in the correct order?
a)
S; G1; G2; M
b)
G1; S; G2; M
c)
M; G2; S; G1
d)
G2; S; M; G2
34.
The causes of cancer may include which of the following?
a)
environmental influences
b)
UV radiation
c)
viruses
d)
all of these
35.
What is a term for programmed cell death?
a)
apoptosis
b)
necrosis
c)
cell death
d)
doom
36.
________________is a critical point where stop and go signals can regulate the cycle
a)
Metastasis
b)
Checkpoint
c)
Malignant
d)
Benign
37.
Which of the following is NOT a reason we need mitosis.
a)
Growth
b)
Recovering from injuries
c)
Replacement of dead cells
d)
Reproducing
38.
Which of the following is not a way mutations occur in cellular DNA?
a)
UV radiation
b)
Genetics
c)
DNA repair proteins not working correctly
d)
Extreme cold
39.
Carcinogen is a substance that induces cancer and it could include: 
a)
Physical agent
b)
Chemical agent
c)
Viral agent
d)
All
40.
Cancer can sometimes be contagious.
a)
True
b)
False
41.
Cancer cells can break away from a malignant tumor and enter the bloodstream or lymphatic system.
a)
True
b)
False
42.

The passage of a cell through the stages of the cell cycle is controlled by protein kinases that phosphorylate many different proteins at appropriate times. What are these protein kinases called?

a)

Cdk activating kinases

b)

Cyclin-dependent kinases

c)

Cyclins

d)

Tyrosine kinases

43.

At which cell cycle checkpoint is the cell cycle halted if the cell's DNA is damaged?

a)

G1 - S

b)

S - G2

c)

G2 - M

d)

G0 - G1

44.

Cyclin dependent kinases which control progression through cell cycle checkpoints are fully activated by which of the following:

a)

binding to cyclins.

b)

phosphorylation by Cdk activating protein kinase.

c)

binding to cyclin, plus phosphorylation by a Cdk activating protein kinase.

d)

phosphorylation by a tyrosine kinase.

45.

Each cyclin dependent kinase (Cdk) is activated by a specific cyclin and works at one specific checkpoint in the cell cycle. True or false?

a)

True

b)

False

46.

Passage through which checkpoint is the step which commits the cell to proceed through to mitosis and cell division?

a)

G1 to S.

b)

S to G2.

c)

G2 to M.

d)

M to G1.

47.

Number of mitotic divisions required to produce 128 cells from a single cell is

a)

7

b)

8

c)

16

d)

32

48.

A cell divides every one minute. At this rate of division, it can fill a 100ml of beaker in one hour. How much time does it take to fill a 50ml beaker?

a)

30 min

b)

60 min

c)

59 min

d)

1 min

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