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The Central Dogma

Total questions: 30

Worksheet time: 18mins

Name
Class
Date
1.
What is the complimentary mRNA sequence to the DNA sequence A-T-T-G-C-A.
a)
T-A-A-C-G-T
b)
U-A-A-C-G-T
c)
U-A-A-C-G-U
d)
T-A-A-G-C-U
2.
Which defines a codon in DNA or mRNA?
a)
pair of nucleic acid and sugar
b)
pair of phosphate and sugar
c)
three-base code
d)
two-base code
3.
The "central dogma" states that genetic information flows from 
a)
Protein-->mRNA-->DNA
b)
Protein-->DNA-->mRNA
c)
mRNA-->DNA-->Protein
d)
DNA-->mRNA-->Protein
4.
Transcription takes place in the 
a)
cytoplasm
b)
ribosome
c)
mitochondrion
d)
nucleus
5.
Translation occurs in the
a)
nucleus
b)
mitochondria
c)
cytoplasm
d)
golgi apparatus
6.

Assembles RNA during transcription

a)

RNA Polymerase

b)

DNA Polymerase

c)

Primase

d)

Ligase

7.

This is the process by which double stranded DNA produces single stranded RNA:

a)

Photosynthesis

b)

Translation

c)

Pollination

d)

Transcription

8.

The start codon is _______:

a)

AUG

b)

GGG

c)

UCG

d)

AAU

9.

The DNA sequence UAGCGAUUACGU is part of a gene. How many amino acids are coded for by this sequence?

a)

20

b)

4

c)

8

d)

12

10.

What is the role of tRNA?

a)

To treat the DNA strand

b)

To transfer codons

c)

To transfer amino acids

d)

To tackle mutations

11.

When reading the codon chart, which molecule do you reference?

a)

DNA

b)

mRNA

c)

tRNA

d)

rRNA

12.

What enzyme does transcription use?

a)

DNA polymerase

b)

ligase

c)

RNA polymerase

d)

helicase

13.

The stage of translation when the ribosome connects to the mRNA and the start codon enters the A site is called

a)

initiation

b)

elongation

c)

termination

d)

protein synthesis

14.

The stage of translation when amino acids are being linked one after another by peptide bonds as the ribosome moves down the mRNA is called

a)

initiation

b)

elongation

c)

termination

d)

protein synthesis

15.

In order for a chain of amino acids to become a protein, it must

a)

be folded into a specific shape

b)

enter the nucleus for modification

c)

have a substrate bonded to it at all times

d)

be replicated by polymerase

16.

RNA has what base that is instead of thymine?

a)

guanine

b)

adenine

c)

thymine

d)

uracil

17.

RNA contains which sugar?

a)

deoxyribose

b)

Ribose

c)

glucose

d)

fructose

18.

What enzyme does transcription use?

a)

DNA polymerase

b)

ligase

c)

RNA polymerase

d)

helicase

19.

Which RNA brings amino acids?

a)

rRNA

b)

tRNA

c)

mRNA

20.

Which RNA carries the message?

a)

mRNA

b)

rRNA

c)

tRNA

21.
What is occurring in this picture?
a)
Translation
b)
Replication
c)
Translocation
d)
Transcription
22.
Which RNA bases would pair with TACGAA in transcription? 
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
23.
What would be the tRNA anticodon for the mRNA codon CAG?
a)
GTC
b)
GUC
c)
CUG
d)
CAG
24.
Which phrase best describes translation?
a)
converts mRNA into a polypeptide
b)
catalyzes bonds between amino acids
c)
produces RNA from DNA molecules
d)
recycles tRNA molecules for reuse
25.
How many amino acids are coded for by this sequence of nucleotides:
ATG GGA ACT CCA
a)
4
b)
2
c)
6
d)
12
26.
Which phase of which process does this picture show?
a)
Transcription
b)
Translation
c)
Replication
27.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
28.
Which of the following would be a nucleotide found in DNA
a)
Ribose + phosphate + uracil
b)
Deoxyribose + phosphate + uracil  
c)
Deoxyribose + phosphate + adenine
d)
Ribose + phosphate + adenine
29.
Using the codon identify the amino acid sequence:
AUG-CCA-GUA-GGG-UAA
a)
MET-HIS-ALA-GLY-STOP
b)
MET-PRO-GLY-VAL-STOP
c)
MET-PRO-VAL-GLY-STOP
d)
MET-THR-SER-ASP-STOP
30.
What is this a picture of?
a)
mRNA
b)
tRNA
c)
rRNA
d)
pRNA

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