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WorksheetsCh3a-b - Human Microbiome in Health & Disease
Total questions: 32
Worksheet time: 16mins
Microbes are ubiquitous, this means that they are:
found everywhere
able to communicate
photosynthesizers
pathogenic
The microbes that colonize humans are collectively referred to as the:
organ system
human microbiome
organic molecules
2nd skin
More than 2% of microbes are pathogenic.
True
False
Microbes that only cause disease under certain circumstances are called:
pathogens
nonpathogens
opportunists
viruses
Bacteria responsible for the creation and maintenance of atmospheric oxygen:
Bacteroidetes
Firmicutes
Cyanobacteria
Escherichia
Bacteria are alive:
True
False
Groups of identical cells that grow from a single bacterial cell.
colonies
biofilms
autoinducers
nucleoids
Layers of microbial cells that stick to surfaces and each other.
colonies
biofilms
autoinducers
nucleoids
Quorum sensing is:
viral communication
bacterial communication
bacterial reproduction
viral reproduction
Bacterial signal proteins released into the environment for communication with other bacterial cells.
autoinducers
positive feedback signals
hydrolyzers
upregulators
When bacterial population size ______, autoinducer concentration _______.
increases; increases
increases; decreases
decreases; increases
decreases; decreases
Different species of bacteria can communicate with one another using autoinducers.
True
False
Unlike eukaryotes, prokaryotes contain:
ribosomes
cytoplasm
nucleoid
cell membranes
Organization trying to characterize and analyze the role of microbes in human health and disease:
Human Microbiome Project
Human Genome Project
World Wildlife Federation
Metagenomic Society of America
Analysis of mixed DNA from a microbiome sample used to identify species and common genes.
Metagenomics
Polymorphism
SDS-PAGE
Deoxyribose nucleic acids
Which of the following areas is considered a common microbiome (choose all that apply):
Nasal passages
Oral cavity
Skin
GI tract
Urogenital tract
Each person has a common core of microbes and a unique set that is determined by your environment and your biochemistry.
True
False
The two major phyla of bacteria in the microbiome are:
Bacteroidetes; Firmicutes
Escherichia; Firmicutes
Bacteroidetes; Enterobactericeae
Staphylococcus; Escherichia
The gut microbiome trains what type of immune cells:
antigen presenting cells
red blood cells
sickle cells
nervous cells
Macrophages are immune cells that:
phagocytize intracellular pathogens
phagocytize extracellular pathogens
Natural killer cells are immune cells that:
kill intracellular pathogens
kill extracellular pathogens
Some bacteria release _________, poisons that specifically target neurons.
neurotoxins
autoinducers
inducers
bacteriocins
A disbalance in the microbiome that affects homeostasis is called:
disease
malnutrition
dysbiosis
obesity
Any compound that stimulates the growth of beneficial microorganisms:
Probiotic
Prebiotic
Carbohydrate
Organic molecule
Non-digestible carbohydrates (nonliving) that serve as food for normal healthy bacteria:
Probiotics
Prebiotics
Monosaccharides
Triglycerides
Drugs that destroy or inhibit bacterial growth:
NSAIDs
toxic
cholinesterase inhibitors
antibiotics
Antibiotic resistance is caused by:
genetic mutations that make bacteria resistant to specific drugs
genetic mutations that make humans resistant to specific drugs
Antibiotic resistance can cause new strains of bacteria:
True
False
Human immune cells secrete ___________ that target microbial ____________.
antigens; antibodies
antibodies; antigens
Which of the following is NOT a benefit of the gut microbiome that helps maintain homeostasis?
regulating neuro-chemical pathways
preventing colonization by pathogenic bacteria
quorum sensing to up-regulate pathogenic bacteria
training antigen-presenting cells of the immune system
Upregulation of virulent genes by bacteria occurs:
during transcription
when bacterial population density is low
within the microbiome
within biofilms
Probiotics should (choose all that apply):
produce organic acids
provide food for the microbiome
increase human immunoglobulins (IgA)
destroy toxins
