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Ch3a-b - Human Microbiome in Health & Disease

Total questions: 32

Worksheet time: 16mins

Name
Class
Date
1.

Microbes are ubiquitous, this means that they are:

a)

found everywhere

b)

able to communicate

c)

photosynthesizers

d)

pathogenic

2.

The microbes that colonize humans are collectively referred to as the:

a)

organ system

b)

human microbiome

c)

organic molecules

d)

2nd skin

3.

More than 2% of microbes are pathogenic.

a)

True

b)

False

4.

Microbes that only cause disease under certain circumstances are called:

a)

pathogens

b)

nonpathogens

c)

opportunists

d)

viruses

5.

Bacteria responsible for the creation and maintenance of atmospheric oxygen:

a)

Bacteroidetes

b)

Firmicutes

c)

Cyanobacteria

d)

Escherichia

6.

Bacteria are alive:

a)

True

b)

False

7.

Groups of identical cells that grow from a single bacterial cell.

a)

colonies

b)

biofilms

c)

autoinducers

d)

nucleoids

8.

Layers of microbial cells that stick to surfaces and each other.

a)

colonies

b)

biofilms

c)

autoinducers

d)

nucleoids

9.

Quorum sensing is:

a)

viral communication

b)

bacterial communication

c)

bacterial reproduction

d)

viral reproduction

10.

Bacterial signal proteins released into the environment for communication with other bacterial cells.

a)

autoinducers

b)

positive feedback signals

c)

hydrolyzers

d)

upregulators

11.

When bacterial population size ______, autoinducer concentration _______.

a)

increases; increases

b)

increases; decreases

c)

decreases; increases

d)

decreases; decreases

12.

Different species of bacteria can communicate with one another using autoinducers.

a)

True

b)

False

13.

Unlike eukaryotes, prokaryotes contain:

a)

ribosomes

b)

cytoplasm

c)

nucleoid

d)

cell membranes

14.

Organization trying to characterize and analyze the role of microbes in human health and disease:

a)

Human Microbiome Project

b)

Human Genome Project

c)

World Wildlife Federation

d)

Metagenomic Society of America

15.

Analysis of mixed DNA from a microbiome sample used to identify species and common genes.

a)

Metagenomics

b)

Polymorphism

c)

SDS-PAGE

d)

Deoxyribose nucleic acids

16.

Which of the following areas is considered a common microbiome (choose all that apply):

a)

Nasal passages

b)

Oral cavity

c)

Skin

d)

GI tract

e)

Urogenital tract

17.

Each person has a common core of microbes and a unique set that is determined by your environment and your biochemistry​.

a)

True

b)

False

18.

The two major phyla of bacteria in the microbiome are:

a)

Bacteroidetes; Firmicutes

b)

Escherichia; Firmicutes

c)

Bacteroidetes; Enterobactericeae

d)

Staphylococcus; Escherichia

19.

The gut microbiome trains what type of immune cells:

a)

antigen presenting cells

b)

red blood cells

c)

sickle cells

d)

nervous cells

20.

Macrophages are immune cells that:

a)

phagocytize intracellular pathogens

b)

phagocytize extracellular pathogens

21.

Natural killer cells are immune cells that:

a)

kill intracellular pathogens

b)

kill extracellular pathogens

22.

Some bacteria release _________, poisons that specifically target neurons.

a)

neurotoxins

b)

autoinducers

c)

inducers

d)

bacteriocins

23.

A disbalance in the microbiome that affects homeostasis is called:

a)

disease

b)

malnutrition

c)

dysbiosis

d)

obesity

24.

Any compound that stimulates the growth of beneficial microorganisms​:

a)

Probiotic

b)

Prebiotic

c)

Carbohydrate

d)

Organic molecule

25.

Non-digestible carbohydrates (nonliving) that serve as food for normal healthy bacteria​:

a)

Probiotics

b)

Prebiotics

c)

Monosaccharides

d)

Triglycerides

26.

Drugs that destroy or inhibit bacterial growth:

a)

NSAIDs

b)

toxic

c)

cholinesterase inhibitors

d)

antibiotics

27.

Antibiotic resistance is caused by:

a)

genetic mutations that make bacteria resistant to specific drugs

b)

genetic mutations that make humans resistant to specific drugs

28.

Antibiotic resistance can cause new strains of bacteria:

a)

True

b)

False

29.

Human immune cells secrete ___________ that target microbial ____________.

a)

antigens; antibodies

b)

antibodies; antigens

30.

Which of the following is NOT a benefit of the gut microbiome that helps maintain homeostasis?

a)

regulating neuro-chemical pathways

b)

preventing colonization by pathogenic bacteria

c)

quorum sensing to up-regulate pathogenic bacteria

d)

training antigen-presenting cells of the immune system

31.

Upregulation of virulent genes by bacteria occurs:

a)

during transcription

b)

when bacterial population density is low

c)

within the microbiome

d)

within biofilms

32.

Probiotics should (choose all that apply):

a)

produce organic acids

b)

provide food for the microbiome

c)

increase human immunoglobulins (IgA)

d)

destroy toxins