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SLS3010 neurodevelopment

Total questions: 12

Worksheet time: 6mins

Name
Class
Date
1.

Gastrulation describes the formation of which three structures?

a)

Endoderm, ectoderm and mesoderm

b)

Forebrain, midbrain and hindbrain

c)

Prosencephalon, mesencephalon and rhombencephalon

d)

Primitive streak, Hensen's node and notochord

2.

What is released from Henson's node to initiate neural differentiation?

a)

BMP-2

b)

BMP-4

c)

Chordin

d)

Henson protein 1

3.

What is the name of the structure indicated by the arrow?

a)

Neural crest

b)

Notochord

c)

Neural tube

d)

Epidermis

4.

Hox gene expression is controlled by a gradient of which substance?

a)

NGF

b)

Noggin

c)

Chordin

d)

Retinoic acid

5.

At six weeks of development, the forebrain (procencephalon) divides into which two secondary vesicles?

a)

Diencephalon and Mesencephalon

b)

Telencephalon and diencephalon

c)

Metencephalon and Myelencephalon

d)

Pontine flexure and myelencephalon

6.

In early development all the cells of the neuroepithelium are stem cells

a)

True

b)

False

7.

Neuronal migration occurs along which type of glial cells?

a)

Astrocytes

b)

oligodendrocytes

c)

Radial glial cells

d)

Microglia

8.

What is A pointing to?

a)

Microtubules

b)

F-actin

c)

Neurofilaments

d)

G-actin

9.

Apoptosis is a common feature of neural development.

a)

True

b)

False

10.

Proneural cluster cells producing the highest amount of Delta will...

a)

Win the race to become neuroblasts

b)

Supress their neighbours' proneural genes

c)

Stimulate their neighbours' proneural genes

d)

Lose the race to become neuroblasts

e)

Become epidermoblasts

11.

Success, from an evolutionary standpoint, does not depend on brain size

a)

True

b)

False

12.

Adaptive specialisations:

a)

Helped the development of social interactions in primates

b)

Include the over representation of the fingers and lips of the human sensory motor cortex

c)

Represent a disproportionately large area of cortex relative to the rest of the body surface

d)

Could explain behavioural differences between closely related species

e)

All of the above