WorksheetsModule 4: Inorganic Compounds of Biological and Pharmaceutic
Total questions: 50
Worksheet time: 25mins
frequently employed in the conversion of drugs to chemical forms convenient to their product formulation
Acids and Bases
Buffers
Antioxidants
Water
maintain the pH of various formulations within prescribed limits
Acids
Bases
Buffers
composed of boric acid and sodium carbonate with potassium chloride in purified water.
Pantin Buffer
Atkin’s Buffer
Feldman’s Buffer
Gifford’s buffer
contains boric acid and sodium carbonate with sodium chloride in purified water.
Feldman’s Buffer
Gifford’s buffer
Atkin’s and Pantin Buffer
composed of boric acid and sodium borate with sodium chloride in purified water.
Gifford’s buffer
Atkin’s and Pantin Buffer
Feldman’s Buffer
prevent oxidative decomposition of pharmaceutically active components
Antioxidant
Water
Buffer
Acids
bicarbonates
Temporary
Permanent
sulfates and chlorides
Permanent
Temporary
used as solvent and is used to make several official solution, tinctures and extracts.
Water USP
Purified Water USP
Water for Injection USP
Sterile Water for Injection
obtained by distillation or by ion exchange treatment. The method of preparation should be
Sterile Water
Water USP
Purified Water
Water for injection
purified by distillation. It must pass pyrogen test. It is intended for use as a solvent for the preparation of parenteral solutions. It must be stored below 4oC or above 37oC.
Water USP
Water for Injection
Sterile Water
is a sterile water for injection containing one or more suitable antimicrobial agents (benzyl alcohol). It is used for compounding small volumes of parenterals for IM injection.
Bacteriostatic Water for Injection
Water for Injection
Sterile Water for Injection USP
is water for injection sterilized and suitably packaged which contains no antimicrobial agents. It is used for extemporaneous compounding of parenterals for either intravenous or intramuscular injection.
Sterile for Injection USP
Water USP
Purified Water USP
decreases coefficient of expansion in pyrex glass.
Lead
Boron
Magnesium
gives brown light resistant glass.
Potassium
Boron
Lead
added to increase refractive index
Lead
Boron
Magnesium
a material that softens gradually over a temperature rather than melting sharply.
Glass
Type II
Vitreous Material
glass makes use of water attack test.
Type II
Boron
Glass
major extracellular anion
Chloride
Phosphate
Bicarbonate
principal anion of the intracellular fluid component
Boron
Biphosphate
Phosphate
2nd most prevalent anion in the extracellular fluid.
Bicarbonate
Boron
Biphosphate
principal cation in the extracellular fluid
Sodium
Potassium
Chloride
major intracellular cation
Potassium
Phosphate
Chloride
1% is found in intracellular fluid especially for blood clotting
Calcium
Biphosphate
Chloride
Bicarbonate
2nd most plentiful cation in the intracellular fluid
Mg
Na
Cl
constituent of thyroxin & triiodothyronine
Iodine
Iron
Zinc
Selenium
constituent of insulin, carbonic anhydrase & lactic dehydrogenase
Zinc
Copper
Iron
for the formation of hemoglobin & constituent of oxides enzymes (tyrosinase)
Selenium
Boron
Copper
Chloride
constituent of vitamin B12
Cobalt
Copper
Chromium
cofactor for a number of enzymes like arginase, carboxylase & kinases
Cobalt
Manganese
Sodium
constituent of proteins, mucopolysaccharides, heparin, biotin, thiamine & lipoic acid
Chromiun
Boron
Sulfur
involved in carbohydrate utilization
Carbon
Chromium
Copper
constituent of xanthine oxidase & aldehyde oxidase
Molybdenum
Chromium
Selenium
constituent of factor 3 acts with Vitamin E to prevent liver necrosis.
Selenium
Molybdenum
Chromium
antocarcinogenic agent
Fluoride
Bromide
Mercury
cathartic, diuretic, antiseptic, disinfectant
Fluoride
Boron
Mercury
Arsenic
sedative (0.2 – 2g) & CNS depressant, Hypnotic (4 - 8g)
Copper
Chromium
Bromide
depressant for epilepsy
Argon
Bromide
Mercury
treatment of hypomanic and manic states
Lithium
Gold
Silver
treatment of lupus erythematosus or rheumatoid arthritis
Iodine
Bronze
Silver
Gold
astringent, antiseptic and deodorant
Aluminum
Gold
Selenium
Bromine
antiseptic, astringent, protein precipitant
Bronze
Silver
Gold
as bromide- sedative; as chloride – desensitizing agent
Strontium
Gold
Bromine
Products for altering gastric pH (Antacid, Acidifier)
Gastro Intestinal Agents
Antacids
Gastric Antacids
Taken after meals
Acids
Bases
Before meals
Bases
Acids
Less than 0.9 and used for dehydration
Hypotonic
Hypertonic
Isotonic
More than 0.9 use to cure edema
Isotonic
Hypertonic
Hypotonic
0.9% NaCl use for water retention
Isotonic
Hypertonic
Hypotonic
Softest mineral
Talc
Magnesium Oxide
Bromide
Potassium
