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DNA history, structure and replication

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Erwin Chargaff's rule of base pairing states that:

a)

adenine pairs with thymine and guanine pairs with cytosine

b)

adenine pairs with guanine and thymine pairs with cytosine

c)

purines pair with pyrimidines

d)

pyrimidines pair only with pyrimidines

2.

Rosanlind Franklin's x-ray diffraction image of her study of DNA was noticed by Watson and Crick and led them to model what they thought the shape and structure of DNA was. What was that shape?

a)

the double helix

b)

the single strand

c)

the sugar and phosphate

d)

the four nitrogen bases

3.

Thymine, adenine, guanine, cytosine, and uracil are classified as:

a)

sugars

b)

codons

c)

nitrogen bases

d)

nucleotides

4.

What is the backbone of this DNA molecule made of?

a)

sugars

b)

nitrogen bases

c)

sugar and phosphate

d)

sugar and nitrogen bases

5.

What type of bonds hold together nitrogen bases?

a)

water bonds

b)

covalent bonds

c)

peptide bonds

d)

hydrogen bonds

6.

Using the bases on the template strand of DNA, what are the new complimentary bases for replication? Template: AGTCA

a)

AGTCA

b)

TCAGT

c)

UCAGU

d)

TCUGT

7.

What enzyme unzips the DNA strands to allow replication to occur?

a)

polymerase

b)

ligase

c)

helicase

d)

primase

8.

All of the following are differences between DNA and RNA except

a)

they are both nucleic acids

b)

the shape of the strand

c)

the type of sugar

d)

the specific nitrogen bases

9.

Which of the following is not part of a molecule of DNA?

a)

ribose sugar

b)

deoxyribose sugar

c)

nitrogen base

d)

phosphate group

10.

A strand of DNA has these bases: AGCCATGTATAC. What is the complementary DNA strand?

a)

UCGCUACAUAUG

b)

TGCCTAGATATAC

c)

TCGGTACATATG

d)

ACGGATCTATAG

11.

How did Rosalind Franklin's x-ray diffraction image of DNA affect the work of Watson and Crick?

a)

It was used to develop the theory of independent assortment.

b)

It was used to determine the physical structure of DNA.

c)

It was used to determine the four bases that make up DNA.

d)

It was used to show that DNA was the molecule of inheritance.

12.

Semi-conservative replication of DNA refers to the idea that___.

a)

the two strands of DNA molecules run in opposite directions.

b)

each new DNA molecule contains 2 new single RNA strands.

c)

each half of the original DNA molecule is joined with a new complementary DNA strand.

d)

DNA molecules need to unwind before duplication begins.

13.

RNA from a chipmunk is compared to RNA from a worm. Both will contain:

a)

the sugar ribose and the base thymine

b)

the sugar dexoyribose and the base thymine

c)

the sugar deoxyribose and the base uracil

d)

the sugar ribose and the base uracil

14.

Which nitrogenous base is normally used in the synthesis (making) of RNA but not in the synthesis (making) of DNA?

a)

uracil

b)

adenine

c)

guanine

d)

cytosine

15.

The structure of DNA is described as a ________ formed by two strands of nucleotides.

a)

protein molecule

b)

double helix

c)

polymerase chain

d)

single spiral