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The Central Dogma

Total questions: 45

Worksheet time: 34mins

Name
Class
Date
1.
In RNA, Uracil pairs with ______. 
a)
cytosine
b)
adenine
c)
guanine
d)
thymine
2.
The process to go from DNA to mRNA is _______
a)
translation
b)
transcription
c)
replication
3.
The process to go from mRNA to a protein is called ____
a)
transcription
b)
rRNA
c)
replication
d)
translation
4.
DNA holds the code for
a)
lipids
b)
carbohydrates
c)
protein
d)
sugar
5.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
6.
The main function of tRNA is to...
a)
carry a message that, when translated, forms proteins
b)
form a portion of ribosomes
c)
string together complementary RNA and DNA strands
d)
bring amino acids from the cytoplasm to the ribosomes
7.
What amino acid is represented by the codon UUA?
a)
Phenylalanine
b)
Tyrosine
c)
Leucine
d)
Stop codon
8.
What process is going on in this photo? 
a)
Transcription 
b)
Translation 
c)
Replication 
d)
All the above 
9.
Which component of DNA determines the traits of an organism? 
a)
Nitrogen Bases
b)
Sugar-Phosphate Backbone
c)
Hydrogen bonds
10.

What is the location in the cell for translation?

a)

nucleus

b)

mitochondria in cytoplasm

c)

ribosome in cytoplasm

d)

chloroplast in cytoplasm

11.
What is the three base sequence of mRNA that codes for a single amino acid?
a)
Anticodon
b)
Codon
c)
Protein
12.
What is the location in the cell for transcription?
a)
nucleus
b)
cytoplasm
c)
ribosome
d)
mitochondria
13.
Translation is the process where
a)
mRNA is created in the Nucleus
b)
mRNA is decoded to form a protein 
c)
glucose molecules are made
d)
is where lipids are synthesised
14.
Does the order of amino acids in a protein matter?
a)
YES!
b)
NO!
15.

What process is happening in the diagram?

a)

transcription

b)

translation

c)

dna replication

d)

mitosis

16.
This is the triplet of bases on the end of a tRNA molecule
a)
Anticodon
b)
Codon
c)
Protein
17.

DNA is the template for

a)

amino acids

b)

tRNA

c)

mRNA

d)

sugars

18.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
19.
The main function of tRNA is to...
a)
carry a message that, when translated, forms proteins
b)
form a portion of ribosomes
c)
string together complementary RNA and DNA strands
d)
bring amino acids from the cytoplasm to the ribosomes
20.
What amino acid is represented by the codon UUA?
a)
Phenylalanine
b)
Tyrosine
c)
Leucine
d)
Stop codon
21.

What is the three base sequence of mRNA that codes for a single amino acid?

a)

Anticodon

b)

Codon

c)

Protein

d)

DNA

22.
What are the backbones (sides) of the DNA structure made up of?
a)
repeating phosphates and sugars
b)
nitrogen bases
c)
nucleotides
d)
adenine and thymine
23.
Which is the mRNA molecule that would be transcribed from this DNA template:
TGGCAAGTACGT
a)
ACCGTTCATGCA
b)
UGGCAAGUACGU
c)
UCCGUUCUUGCU
d)
ACCGUUCAUGCA
24.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
25.
How many amino acids are coded for by this sequence of nucleotides:
ATG GGA ACT CCA
a)
4
b)
2
c)
6
d)
12
26.

A polypeptide is a sequence of ____________________ held together by a ______________ bond.

a)

amino acids; peptide

b)

fatty acids; ionic

c)

proteins; hydrogen

d)

fatty acids; covalent

27.

How do you know when to begin translating a strand of mRNA?

a)

look for AUG

b)

start at the beginning

c)

look for ATG

d)

when Ms. H tells me to

28.
Does the order of amino acids in a protein matter?
a)
YES!
b)
NO!
29.

A DNA nucleotide may be made up of a phosphate group, along with

a)

deoxyribose sugar and uracil

b)

ribose sugar and cytosine

c)

deoxyribose sugar and thymine

d)

ribose sugar and adenine

30.

The important enzyme related with transcription is;

a)

gyrase

b)

DNA polymerase

c)

RNA polymerase

d)

ligase

31.

There are 3 types of

a)

DNA

b)

RNA

32.
The diagram below represents a portion of a DNA molecule. The letters represent different types of 
a)
sugar molecules
b)
nitrogen bases
c)
enzymes
d)
proteins
33.
Which of the following carries amino acids to the site of protein synthesis? 
a)
mRNA
b)
rRNA
c)
tRNA
d)
nRNA
34.
At what point in the cell cycle does DNA replication occur and why?
a)
before a cell divides, to provide each of the two resulting cells with a complete set of DNA instructions
b)
before a cell divides, to ensure that the DNA will fit into the resulting cells
c)
during cell division, to ensure that the DNA will fit into the resulting cells
d)
after a cell divides, to provide each of the two resulting cells with a complete set of DNA instructions 
35.
Which choice describes DNA after replication has taken place?
a)
one molecule with two original strands and one molecule with two new strands
b)
two molecules, each with one original and one new strand
c)
two molecules, each with two new strands
d)
 two molecules, each with two old strands
36.
If the percentage of DNA is made of 30% Thymine, what is the correct percentage of Guanine?
a)
30
b)
15
c)
20
d)
60
37.
Replicate the following strand of DNA: 
AATCATGGA
a)
AATCATGGA
b)
TTAGTACCT
c)
UUAGUACCU
d)
GGATAUCUA
38.
The enzyme that unzips the DNA to prepare for replication
a)
helicase
b)
replicase
c)
polymerase
d)
synthase
39.
The DNA nucleotide is composed of three parts. Which two components make up the nucleotide backbone?
a)
ribose sugar and base
b)
ribose sugar and phosphate group
c)
nitrogen base and deoxyribose sugar
d)
deoxyribose sugar and phosphate group
40.
What is responsible for holding the two strands of the DNA double helix together?
a)
hydrogen bonds
b)
alleles
c)
London dispersion forces
d)
deoxyribose sugars
41.
What are the 4 nitrogen bases?
a)
adenine, thymine, cytoplasm, and guanine
b)
adenine, thymine cytosine, and guanine
c)
adenine, thymine, cytosine, and gylcerol
d)
adenine, thymine, cytosine, and glucose
42.
Which organelle is DNA usually found in?
a)
cell membrane
b)
vacuole
c)
chloroplast
d)
nucleus
43.
Describes the twisted ladder-like shape of a DNA molecule
a)
Nitrogen Base
b)
Hexagon
c)
Double Helix
44.
After analyzing a sample of DNA, a scientist recorded the data shown in the table. What percentage of the DNA sample is cytosine?
a)
22%
b)
25%
c)
28%
d)
56%
45.
Name this structure
a)
double helix
b)
nucelotide
c)
twisted ladder
d)
hydrogen bond