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DNA, Replication, Central Dogma

Total questions: 20

Worksheet time: 15mins

Name
Class
Date
1.
Which do DNA and RNA have in common?
a)
Both are double stranded.
b)
Both contain ribose molecules.
c)
Both contain phosphate groups.
d)
Both contain uracil.
2.
If the structure of DNA were likened to a ladder, what would make up the “supporting structure” (not the “rungs”) of the ladder?
a)
amino acids and sugars
b)
nucleotide bases, including thymine
c)
nucleotide bases, including uracil
d)
sugar-phosphate molecules
3.
What is the complimentary mRNA sequence to the DNA sequence A-T-T-G-C-A.
a)
T-A-A-C-G-T
b)
U-A-A-C-G-T
c)
U-A-A-C-G-U
d)
T-A-A-G-C-U
4.

Which defines a codon in mRNA?

a)

pair of nucleic acid and sugar

b)

pair of phosphate and sugar

c)

three-base code

d)

two-base code

5.
What are the building blocks of proteins called?
a)
DNA
b)
RNA
c)
Ribosomes
d)
Amino Acids
6.
The "central dogma" states that genetic information flows from 
a)
Protein-->mRNA-->DNA
b)
Protein-->DNA-->mRNA
c)
mRNA-->DNA-->Protein
d)
DNA-->mRNA-->Protein
7.
Transcription takes place in the 
a)
cytoplasm
b)
ribosome
c)
mitochondrion
d)
nucleus
8.
The anticodon of a particular tRNA molecule is 
a)
complementary to the corresponding mRNA codon.
b)
complementary to the corresponding triplet in rRNA.
c)
the part of tRNA that bonds with a specific amino acid.
d)
catalytic, making the tRNA a ribozyme.
9.
The parts of a gene that do NOT code for amino acids in a protein are called
a)
introns
b)
exons
c)
codons
d)
anticodons
10.

The production of mature mRNA in eukaryotes involves

a)

cutting introns out and splicing exons together

b)

adding the 5' cap

c)

adding the 3' poly A tail

d)

all of these are correct

11.
Translation occurs:
a)
Outside of the Nucleus
b)
Inside of the Nucleus
12.
Translation is crucial to the process of making proteins. Which statement best describes what takes place during translation? 
a)
A copy of chromosomal DNA is created 
b)
Information in mRNA is converted into a sequence of amino acids in a protein 
c)
A RNA copy of a DNA strand is made.
d)
Instructions from DNA in the nucleus are brought to the cytoplasm 
13.
Smaller segments of RNA nucleotides that transport amino acids to the ribosomes.
a)
mRNA
b)
tRNA
c)
rRNA
d)
DNA
14.

Which enzyme joins the Okazaki fragments in the lagging strand?

a)

Helicase

b)

DNA Polymerase

c)

Ligase

d)

Primase

15.

This picture is illustrating the ____ nature of DNA.

a)

antiparallel

b)

semiconservative

c)

helical

d)

radioactive

16.

How do the leading and the lagging strands differ?

a)

The leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.

b)

The leading strand is synthesized at twice the rate of the lagging strand.

c)

The leading strand is synthesized in short fragments that are ultimately stitched together, whereas the lagging strand is synthesized continuously.

d)

The leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5' end.

17.

What are the monomers of DNA?

a)

amino acids

b)

nucleotides

c)

fatty acids

d)

simple sugars

18.

What enzyme keeps DNA from overwinding ahead of replication forks?

a)

Primase

b)

Topoisomerase

c)

Single-Stand Binding Protein

d)

Helicase

19.

What is the function of the poly-A tail in mRNA?

a)

to add modified guanine to the 3' end of the mRNA

b)

to indicate the site of translational termination

c)

to code for the binding of RNA polymerase to the DNA

d)

to help protect the mRNA from degradation by hydrolytic enzymes

20.

If a sample of DNA contains 20% Thymine nucleotides, what percentage of the sample would be Cytosine nucleotides?

a)

20%

b)

30%

c)

40%

d)

60%