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Cell Signaling

Total questions: 15

Worksheet time: 13mins

Name
Class
Date
1.

In cell signaling, how is the flow of specific ions

regulated?

a)

Opening and closing of ligand-gated channels

b)

Transduction

c)

Cytoskeleton rearrangement

d)

Endocytosis

2.

Many signal transduction pathways use second messengers to:

a)

transport a signal through the lipid bilayer portion of the plasma membrane.

b)

relay a signal from the outside to the inside of the cell.

c)

relay the message from the inside of the membrane throughout the cytoplasm.

d)

amplify the message by phosphorylating proteins.

3.

Which of the following can activate a protein by transferring a phosphate group to it?

a)

cAMP

b)

G proteins

c)

phosphodiesterase

d)

protein kinase

4.

Of the following, a receptor protein in a membrane that recognizes a chemical signal is most similar to

a)

the active site of an enzyme in the cytoplasm that binds to a specific substrate.

b)

RNA specifying the amino acids in a polypeptide.

c)

genes making up a chromosome.

d)

an enzyme with an optimal pH and temperature for activity.

5.

What could happen to the target cells in an animal that lack receptors for local regulators?

a)

They could compensate by receiving nutrients via an α factor.

b)

They could develop normally in response to neurotransmitters instead.

c)

They could divide but never reach full size.

d)

They would not be able to multiply in response to growth factors from nearby cells.

6.
A signal molecule that binds to a plasma-membrane protein is a
a)
ligand
b)
second messenger
c)
protein kinase
d)
receptor protein
7.
What is a G protein?
a)
specific type of membrane-receptor protein
b)
protein on the cytoplasmic side of a membrane
c)
membrane-bound enzyme
d)
relay protein
8.
What determines whether a cell is a target cell for a particular signal molecule?
a)
phosphorylation cascade
b)
cAMP
c)
signal receptors
d)
phosphatase
9.
Which of the following is a chemical message that usually travels through the bloodstream to target cells?
a)
hormone
b)
local regulator
c)
endocrine cell
10.
The 3 steps of signal transduction in order are
a)
reception, transduction, response
b)
response, transduction, reception
c)
reception, response, transduction
d)
transduction, reception, response
11.

This is an example of

a)

paracrine signaling

b)

endocrine signaling

c)

autocrine signaling

d)

juxtacrine signaling

12.

What is being depicted in the image?

a)

Amplification of the signal molecule

b)

Enzymatic proteins inhibiting process of the signal transduction pathway

c)

Kinase groups adding dimer groups to other enzymes

d)

Diffusion of molecules within the cell due to the signaling molecule

13.

Which letter represents the cell membrane?

a)

A

b)

B

c)

C

d)

D

e)

E

14.

Which letter represents the cell surface receptor protein?

a)

A

b)

B

c)

C

d)

D

e)

E

15.

Which letter represents the ligand?

a)

A

b)

B

c)

C

d)

D

e)

E