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Anti-Arrhythmia Drugs

Total questions: 17

Worksheet time: 9mins

Name
Class
Date
1.

Phase of Action Potential in Cardiac Cells wherein there is inward flux of sodium ions and outflow of potassium ions

a)

0

b)

1

c)

2

d)

3

2.

Class of Anti-Arrhythmia drugs which affects phase 0 of the action potential and prolongs action potential thereby slowing conduction.

a)

1A

b)

1B

c)

1C

d)

2

3.

Phase of action potential of cardiac cells wherein the calcium current inactivates and there is potassium outflow.

a)

1

b)

2

c)

3

d)

4

4.

All of the following statements are correct about the mechanisms of arrhythmia except?

a)

It could result from abnormal automaticity

b)

Due to delayed repolarizations

c)

Re-entry phenomenon

d)

Focal conduction blocks along the pathway of the impulses

5.

Phase of action potential wherein there is a slow influx of calcium current. Also known as the plateau phase.

a)

1

b)

2

c)

3

d)

4

6.

A drug classified as a sodium channel blocker which is better tolerated than quinidine and has no vagolytic or alpha blocking action.

a)

Disopyramide

b)

Morcizine

c)

Procainamide

d)

Lignocaine

7.

Cinchonism is a usual side effect of excessive intake of quinidine. The following symptoms are part of the triad for cinchonism except?

a)

temporary deafness

b)

blindness

c)

rashes

d)

dizziness

8.

Class of drugs which markedly slow down phase 0 of the cardiac action potential. These are also the most potent sodium channel blockers.

a)

1A

b)

1B

c)

1C

d)

2

9.

A common route of administration for amiodarone and atropine.

a)

oral

b)

intravenous

c)

intramuscular

d)

endotracheal

10.

An iodine containing long acting drug which has multiple mechanisms of action and is usually used for both supraventricular and ventricular tachycardia.

a)

Atropine

b)

Verapamil

c)

Amiodarone

d)

Phenytoin

11.

Which of the following is not an adverse effect of high dosages of Procainamide?

a)

hypotension

b)

heart blocks

c)

hypertension

d)

QT prolongation

12.

This is a class of anti-arrhythmia drugs that prolong phase 3 repolarization without altering phase 0. It increases the ADP and prolongs RP by blocking potassium channels.

a)

1C

b)

2

c)

3

d)

4

13.

It is a selective potassium channel blocker with less adverse events. It's only used for atrial fibrillation to convert or normalize the sinus rhythm.

a)

Bretylium

b)

Sotalol

c)

Ibutilide

d)

Dofetilide

14.

A purine nucleotide having short and rapid action. It is also the drug of choice for Paroxysmal Supraventricular Tachycardia.

a)

Atropine

b)

Digitalis

c)

Adenosine

d)

Magnesium Sulfate

15.

A Class 2 drug used to treat and prevent supraventricular arrhythmias especially associated with exercise , emotion, or hyperthyroidism.

a)

Esomolol

b)

Propanolol

c)

Atropine

d)

Adenosine

16.

3 ANSWERS. CHOOSE ALL THAT APPLIES.


Class 1B sodium channel blockers

a)

Encainide

b)

Lignocaine

c)

Propafenone

d)

Mexiletine

e)

Phenytoin

17.

2 ANSWERS. CHOOSE ALL THAT APPLIES.


Class 4: Calcium Channel Blockers

a)

Amiodarone

b)

Propanolol

c)

Verapamil

d)

Digoxin

e)

Diltiazem